1,4-Dithiothreitol

Modify Date: 2025-08-26 18:55:36

1,4-Dithiothreitol structure	Common Name	1,4-Dithiothreitol
	CAS Number	16096-97-2	Molecular Weight	154.251
	Density	1.3±0.1 g/cm3	Boiling Point	364.5±42.0 °C at 760 mmHg
	Molecular Formula	C₄H₁₀O₂S₂	Melting Point	42-44ºC
	MSDS	Chinese USA	Flash Point	174.2±27.9 °C
	Symbol	GHS07	Signal Word	Warning

Use of 1,4-Dithiothreitol

L-Dithiothreitol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Name	L-1,4-dithiothreitol
Synonym	More Synonyms

Description	L-Dithiothreitol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Related Catalog	Research Areas >> Others

Density	1.3±0.1 g/cm3
Boiling Point	364.5±42.0 °C at 760 mmHg
Melting Point	42-44ºC
Molecular Formula	C₄H₁₀O₂S₂
Molecular Weight	154.251
Flash Point	174.2±27.9 °C
Exact Mass	154.012222
PSA	118.06000
LogP	0.07
Vapour Pressure	0.0±1.8 mmHg at 25°C
Index of Refraction	1.579
Storage condition	−20°C

1,4-Dithiothreitol MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: EK1612000

CHEMICAL NAME :: 2,3-Butanediol, 1,4-dimercapto-, L-threo-

CAS REGISTRY NUMBER :: 16096-97-2

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C4-H10-O2-S2

MOLECULAR WEIGHT :: 154.26

WISWESSER LINE NOTATION :: SH1YQYQ1SH -L,THREO

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 179 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 15,600,1972

Symbol	GHS07
Signal Word	Warning
Hazard Statements	H302-H312-H315-H319-H335
Precautionary Statements	P261-P280-P305 + P351 + P338
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xn: Harmful;
Risk Phrases	R21/22
Safety Phrases	26-36/37
RIDADR	UN 3335
WGK Germany	3
RTECS	EK1612000
Hazard Class	9.0
HS Code	2930909090

(4S,5S)-dithian...

CAS#:16096-98-3

~82%

1,4-Dithiothreitol

CAS#:16096-97-2

Literature: Lee, Sang Hyup; Kohn, Harold Heterocycles, 2003 , vol. 60, # 1 p. 47 - 56

Precursor 1
CAS#:16096-98-3 (4S,5S)-dithian...
DownStream 0

HS Code	2930909090
Summary	2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Involvement of epigenetics and EMT-related miRNA in arsenic-induced neoplastic transformation and their potential clinical use.

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The mTOR inhibitor rapamycin synergizes with a fatty acid synthase inhibitor to induce cytotoxicity in ER/HER2-positive breast cancer cells.

PLoS ONE 9(5) , e97697, (2014)

Patients with ER/HER2-positive breast cancer have a poor prognosis and are less responsive to selective estrogen receptor modulators; this is presumably due to the crosstalk between ER and HER2. Fatty...

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Mol. Cancer Res. 13(1) , 161-73, (2015)

The crucial role of tumor-associated fibroblasts (TAF) in cancer progression is now clear in non-small cell lung cancer (NSCLC). However, therapies against TAFs are limited due to a lack of understand...

Cleland reagent chiral

2,3-Butanediol, 1,4-dimercapto-, (2R,3R)-rel-

(2R,3R)-1,4-Disulfanyl-2,3-butanediol

1,4-Dithiothreitol

L-(−)-Dithiothreitol

1,4-Bissulfanylbutane-2,3-diol

DL-1,4-Dimercapto-2,3-dihydroxybutane

(2R,3R)-(-)-2,3-Dihydroxy-1,4-butanedithiol

1,4-Disulfanyl-2,3-butanediol

(R*,R*)-1,4-DIMERCAPTO-2,3-BUTANEDIOL

(2R,3R)-1,4-Disulfanylbutane-2,3-diol

2,3-Butanediol, 1,4-dimercapto-, (2R,3R)-

L-Dithiothreitol

EINECS 240-263-0

(2R*,3S*)-1,4-dimercaptobutane-2,3-diol

dithiothreitol

threo-2,3-Dihydroxy-1,4-butanedithiol

(−)-Cleland's Reagent

(2R*,3S*)-1,4-dimercapto-2,3-butanediol

(2R,3R)-(-)-1,4-Dimercapto-2,3-butanediol

(2R,3R)-1,4-Dimercapto-2,3-butanediol

UNII:T8ID5YZU6Y

L-Cleland's

1,4-Disulfanylbutane-2,3-diol

2,3-Butanediol, 1,4-dimercapto-

(±)-1,4-Dimercapto-2,3-butanediol

(2R,3R)-1,4-dimercaptobutane-2,3-diol

MFCD00064305

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: 1,4-Dithiothreitol
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: 1,4-Dithiothreitol
Price: ￥2958.0/1g ￥9328.0/5g
Purity: 95.0%
Delivery: Inquiry
Contact: Liu jia
Email: 2130147988@qq.com

DC Chemicals Limited
China
Product Name: L-Dithiothreitol
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: L-dithiothreitol
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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