Deruxtecan analog

Modify Date: 2025-08-20 16:36:16

Deruxtecan analog Structure
Deruxtecan analog structure
Common Name Deruxtecan analog
CAS Number 1599440-13-7 Molecular Weight 1034.05
Density 1.48±0.1 g/cm3 Boiling Point 1491.1±65.0 °C
Molecular Formula C52H56FN9O13 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Deruxtecan analog


Deruxtecan analog is a drug-linker conjugate for antibody-drug conjugate (ADC) extracted from patent WO2017002776A1, compound 1.

 Names

Name Deruxtecan analog

 Deruxtecan analog Biological Activity

Description Deruxtecan analog is a drug-linker conjugate for antibody-drug conjugate (ADC) extracted from patent WO2017002776A1, compound 1.
Related Catalog
Target

Drug-linker conjugates for ADC[1]

In Vitro Antibody-drug conjugates deliver anticancer agents selectively and efficiently to tumor tissue and have significant antitumor efficacy with a wide therapeutic window[2].
References

[1]. NOGUCHI, Shigeru, et al. METHOD FOR SELECTIVELY MANUFACTURING ANTIBODY-DRUG CONJUGATE. WO2017002776A1.

[2]. Ogitani Y, et al. Bystander killing effect of DS-8201a, a novel anti-human epidermal growth factor receptor 2 antibody-drug conjugate, in tumors with human epidermal growth factor receptor 2 heterogeneity. Cancer Sci. 2016 Jul;107(7):1039-46.

 Chemical & Physical Properties

Density 1.48±0.1 g/cm3
Boiling Point 1491.1±65.0 °C
Molecular Formula C52H56FN9O13
Molecular Weight 1034.05
InChIKey WXNSCLIZKHLNSG-MCZRLCSDSA-N
SMILES CCC1(O)C(=O)OCc2c1cc1n(c2=O)Cc2c-1nc1cc(F)c(C)c3c1c2C(NC(=O)COCNC(=O)CNC(=O)C(Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)CCCCCN1C(=O)C=CC1=O)CC3
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