N4-OCTADECYLCYTOSINE BETA-D-ARABINOFURANOSIDE
Modify Date: 2024-01-08 00:53:23
N4-OCTADECYLCYTOSINE BETA-D-ARABINOFURANOSIDE structure
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Common Name | N4-OCTADECYLCYTOSINE BETA-D-ARABINOFURANOSIDE | ||
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| CAS Number | 158233-67-1 | Molecular Weight | 495.69500 | |
| Density | 1.16g/cm3 | Boiling Point | 643ºC at 760mmHg | |
| Molecular Formula | C27H49N3O5 | Melting Point | N/A | |
| MSDS | USA | Flash Point | 342.7ºC | |
| Name | 1-[(2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-(octadecylamino)pyrimidin-2-one |
|---|---|
| Synonym | More Synonyms |
| Density | 1.16g/cm3 |
|---|---|
| Boiling Point | 643ºC at 760mmHg |
| Molecular Formula | C27H49N3O5 |
| Molecular Weight | 495.69500 |
| Flash Point | 342.7ºC |
| Exact Mass | 495.36700 |
| PSA | 120.33000 |
| LogP | 4.36240 |
| Vapour Pressure | 3.01E-19mmHg at 25°C |
| Index of Refraction | 1.556 |
| RIDADR | NONH for all modes of transport |
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| WGK Germany | 3 |
| RTECS | UW7370900 |
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Metabolism of the new liposomal anticancer drug N4-octadecyl-1-beta-D-arabinofuranosylcytosine in mice.
Drug Metab. Dispos. 27 , 342-350, (1999) Metabolism and excretion of the new antitumor drug N4-octadecyl-1-beta-D-arabinofuranosylcytosine (NOAC) was investigated in mice. Mice were injected i.v. with tritium-labeled liposomal NOAC (4 microm... |
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Lipophilic arabinofuranosyl cytosine derivatives in liposomes.
Meth. Enzymol. 391 , 58-70, (2005) Highly lipophilic drugs can be used therapeutically only by the addition of possibly toxic solubilizing agents or by development of complex pharmaceutical formulations. One way of overcoming these dis... |
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In vitro activity of liposomal N4octadecyl-1-beta-D-arabinofuranosylcytosine (NOAC), a new lipophilic derivative of 1-beta-D-arabinofuranocylcytosine on biopsized clonogenic human tumor cells and hematopoietic precursor cells.
Invest. New Drugs 19 , 203-210, (2001) N4-octadecyl-1-beta-D-arabinofuranosylcytosine (NOAC) is a new lipophilic derivative of 1-beta-D-arabinofuranosylcytosine (ara-C) with potent antitumor activity against leukemias and solid tumors. In ... |
| N(4)-octadecyl-ara-C,N4-Stearyl-Ara C,NOAC |
| N4-Stearyl-Ara C |
| NOAC |
| N(4)-octadecyl-ara-C |
| N(4)-Octadecyl-1-arabinofuranosylcytosine |
| Alkasar-18 |