Mal-C6-α-Amanitin
Modify Date: 2025-08-27 13:19:04
Mal-C6-α-Amanitin structure
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Common Name | Mal-C6-α-Amanitin | ||
|---|---|---|---|---|
| CAS Number | 1578249-76-9 | Molecular Weight | 1211.34 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C55H78N12O17S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Mal-C6-α-AmanitinMal-C6-α-Amanitin is a drug-linker conjugate for ADC with potent antitumor activity by using α-Amanitin (an RNA polymerase II inhibitor), linked via the ADC linker Mal-C6. |
| Name | Mal-C6-α-Amanitin |
|---|
| Description | Mal-C6-α-Amanitin is a drug-linker conjugate for ADC with potent antitumor activity by using α-Amanitin (an RNA polymerase II inhibitor), linked via the ADC linker Mal-C6. |
|---|---|
| Related Catalog | |
| Target |
Daunorubicins/Doxorubicins |
| References |
[1]. Brian Lannutti,et al. Ror1 antibody immunoconjugates. WO2018237335A1. |
| Molecular Formula | C55H78N12O17S |
|---|---|
| Molecular Weight | 1211.34 |
| InChIKey | AZOYRQMJVHMVBB-HSXFGRQBSA-N |
| SMILES | CCC(C)C1NC(=O)CNC(=O)C2Cc3c([nH]c4cc(OCCCCCCNC(=O)CCCCCN5C(=O)C=CC5=O)ccc34)S(=O)CC(NC(=O)CNC1=O)C(=O)NC(CC(N)=O)C(=O)N1CC(O)CC1C(=O)NC(C(C)C(O)CO)C(=O)N2 |