SB-209670
Modify Date: 2024-01-20 20:56:07
SB-209670 structure
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Common Name | SB-209670 | ||
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| CAS Number | 157659-79-5 | Molecular Weight | 520.53 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C29H28O9 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of SB-209670SB-209670 is an extremely potent and highly specific non-peptide, subnanomolar endothelin (ET) receptor antagonist. SB 209670 selectively inhibits binding of 125I-labeled ET-1 to cloned human ET receptor subtypes ETA and ETB (Ki=0.2 and 18 nM, respectively). SB 209670 produces a dose-dependent reduction in blood pressure in hypertensive rats, protects from ischemia-induced neuronal degeneration in a gerbil stroke model, and attenuates neointima formation following rat carotid artery balloon angioplasty[1]. |
| Name | SB209670 |
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| Synonym | More Synonyms |
| Description | SB-209670 is an extremely potent and highly specific non-peptide, subnanomolar endothelin (ET) receptor antagonist. SB 209670 selectively inhibits binding of 125I-labeled ET-1 to cloned human ET receptor subtypes ETA and ETB (Ki=0.2 and 18 nM, respectively). SB 209670 produces a dose-dependent reduction in blood pressure in hypertensive rats, protects from ischemia-induced neuronal degeneration in a gerbil stroke model, and attenuates neointima formation following rat carotid artery balloon angioplasty[1]. |
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| Related Catalog | |
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| Molecular Formula | C29H28O9 |
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| Molecular Weight | 520.53 |
| SB-209670 |