Avitinib

Modify Date: 2025-08-25 16:25:31

Avitinib structure	Common Name	Avitinib
	CAS Number	1557267-42-1	Molecular Weight	487.529
	Density	1.4±0.1 g/cm3	Boiling Point	N/A
	Molecular Formula	C₂₆H₂₆FN₇O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Avitinib

Avitinib (AC0010) is an irreversible, mutant-selective EGFR inhibitor that effectively inhibits EGFR T790M resistance mutations in non-small cell lung cancer (NSCLC). Abivertinib is also a novel BTK inhibitor.

Name	N-{3-[(2-{[3-Fluoro-4-(4-methyl-1-piperazinyl)phenyl]amino}-7H-pyrrolo[2,3-d]pyrimidin-4-yl)oxy]phenyl}acrylamide
Synonym	More Synonyms

Description	Avitinib (AC0010) is an irreversible, mutant-selective EGFR inhibitor that effectively inhibits EGFR T790M resistance mutations in non-small cell lung cancer (NSCLC). Abivertinib is also a novel BTK inhibitor.
Related Catalog	Research Areas >> Cancer Signaling Pathways >> JAK/STAT Signaling >> EGFR Signaling Pathways >> Protein Tyrosine Kinase/RTK >> EGFR Signaling Pathways >> Protein Tyrosine Kinase/RTK >> Btk
References	[1]. Xu X, Mao L, Xu W, et al. AC0010, an Irreversible EGFR Inhibitor Selectively Targeting Mutated EGFR and Overcoming T790M-Induced Resistance in Animal Models and Lung Cancer Patients. Mol Cancer Ther. 2016;15(11):2586-2597. [2]. Yan X, Zhou Y, Huang S, et al. Promising efficacy of novel BTK inhibitor AC0010 in mantle cell lymphoma. J Cancer Res Clin Oncol. 2018;144(4):697-706.

Description

Related Catalog

Research Areas >> Cancer

Signaling Pathways >> JAK/STAT Signaling >> EGFR

Signaling Pathways >> Protein Tyrosine Kinase/RTK >> EGFR

Signaling Pathways >> Protein Tyrosine Kinase/RTK >> Btk

References

[1]. Xu X, Mao L, Xu W, et al. AC0010, an Irreversible EGFR Inhibitor Selectively Targeting Mutated EGFR and Overcoming T790M-Induced Resistance in Animal Models and Lung Cancer Patients. Mol Cancer Ther. 2016;15(11):2586-2597.

[2]. Yan X, Zhou Y, Huang S, et al. Promising efficacy of novel BTK inhibitor AC0010 in mantle cell lymphoma. J Cancer Res Clin Oncol. 2018;144(4):697-706.

Density	1.4±0.1 g/cm3
Molecular Formula	C₂₆H₂₆FN₇O₂
Molecular Weight	487.529
Exact Mass	487.213196
LogP	3.50
Index of Refraction	1.697
Storage condition	-20℃

N-{3-[(2-{[3-Fluoro-4-(4-methyl-1-piperazinyl)phenyl]amino}-7H-pyrrolo[2,3-d]pyrimidin-4-yl)oxy]phenyl}acrylamide

2-Propenamide, N-[3-[[2-[[3-fluoro-4-(4-methyl-1-piperazinyl)phenyl]amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]phenyl]-

Avitinib

Avi Tini

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Avitinib
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Avitinib
Price: ￥10036.0/1g ￥1256.0/25mg ￥626.0/5mg ￥2516.0/100mg
Purity: 97.0%
Delivery: 2 Day
Contact: Liu jia
Email: 2130147988@qq.com

DC Chemicals Limited
China
Product Name: Avitinib free base
Price: $450.0/100mg $800.0/250mg $1600.0/1g
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

ShangHai DC Chemicals Co.,Ltd
China
Product Name: Avitinib free base
Price: ￥Inquiry/1g
Purity: 98.9%
Delivery: 1 Day
Contact: Tony Lai
Email: order@dcchemicals.com

Shanghai Amole Biotechnology Co., Ltd.
China
Product Name: Avitinib
Price: ￥Inquiry/100mg ￥Inquiry/1g ￥Inquiry/250mg ￥Inquiry/25mg
Purity: 97.0%
Delivery: Inquiry
Contact: Xiyao Wang
Email: 3623107365@qq.com

Get all suppliers and price by the below link:

Avitinib suppliers

Avitinib price

Avitinib

Use of Avitinib

Names

Avitinib Biological Activity

Chemical & Physical Properties

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.