Mangafodipir

Modify Date: 2025-08-25 11:41:46

Mangafodipir Structure
Mangafodipir structure
Common Name Mangafodipir
CAS Number 155319-91-8 Molecular Weight 691.379
Density N/A Boiling Point N/A
Molecular Formula C22H30N4O14P2.Mn Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Mangafodipir


Mangafodipir, hepatocellular-specific contrast agent, is an efficacious inhibitor of CIPN (chemotherapy-induced peripheral neuropath) and other conditions caused by cellular oxidative stress. Mangafodipir shows no negative interference with the tumoricidal activity of chemotherapy[1][2].

 Names

Name Mangafodipir

 Mangafodipir Biological Activity

Description Mangafodipir, hepatocellular-specific contrast agent, is an efficacious inhibitor of CIPN (chemotherapy-induced peripheral neuropath) and other conditions caused by cellular oxidative stress. Mangafodipir shows no negative interference with the tumoricidal activity of chemotherapy[1][2].
Related Catalog
References

[1]. Karlsson JOG, et al. Mangafodipir a Selective Cytoprotectant - with Special Reference to Oxaliplatin and Its Association to Chemotherapy-Induced Peripheral Neuropathy (CIPN). Transl Oncol. 2017 Aug;10(4):641-649.

[2]. Wang C. Mangafodipir trisodium (MnDPDP)-enhanced magnetic resonance imaging of the liver and pancreas. Acta Radiol Suppl. 1998;415:1-31.

 Chemical & Physical Properties

Molecular Formula C22H30N4O14P2.Mn
Molecular Weight 691.379
InChIKey QDQFSBKXQQZVTB-UHFFFAOYSA-L
SMILES Cc1ncc(COP(=O)([O-])[O-])c(CN(CCN(CC(=O)[O-])Cc2c(COP(=O)([O-])[O-])cnc(C)c2O)CC(=O)[O-])c1O.[H+].[H+].[H+].[H+].[Mn+2]
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