Dexamethasone 17-Propionate

Modify Date: 2024-01-11 19:36:44

Dexamethasone 17-Propionate Structure
Dexamethasone 17-Propionate structure
Common Name Dexamethasone 17-Propionate
CAS Number 15423-89-9 Molecular Weight 448.52400
Density 1.28g/cm3 Boiling Point 579.5ºC at 760mmHg
Molecular Formula C25H33FO6 Melting Point N/A
MSDS N/A Flash Point 304.3ºC

 Names

Name [(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.28g/cm3
Boiling Point 579.5ºC at 760mmHg
Molecular Formula C25H33FO6
Molecular Weight 448.52400
Flash Point 304.3ºC
Exact Mass 448.22600
PSA 100.90000
LogP 2.85660
Vapour Pressure 7.68E-16mmHg at 25°C
Index of Refraction 1.567

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
TU3836550
CHEMICAL NAME :
Pregna-1,4-diene-3,20-dione, 9-fluoro-11,21-dihydroxy-16-methyl-17-(1-oxopropoxy)- , (11-beta,16-alpha)-
CAS REGISTRY NUMBER :
15423-89-9
LAST UPDATED :
199806
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C25-H33-F-O6
MOLECULAR WEIGHT :
448.58

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>4 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: -,666,1990
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
36500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: -,666,1990
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
26 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: -,666,1990
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
7600 ug/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: -,781,1995

 Safety Information

HS Code 2915900090

 Customs

HS Code 2915900090
Summary 2915900090 other saturated acyclic monocarboxylic acids and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:5.5% General tariff:30.0%

 Synonyms

Dexamethasone propionate
Pregna-1,4-diene-3,20-dione,9-fluoro-11beta,17,21-trihydroxy-16alpha-methyl-,17-propionate
Dexamethason-17-propionat
Dexamethasone 17-propionate
9-Fluoro-11|A,17,21-trihydroxy-16|A-methyl-pregna-1,4-diene-3,20-dione 17-Propionate
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