4-amino-N-(4-(2-cyanoethynyl)phenyl)butanamide structure
|
Common Name | 4-amino-N-(4-(2-cyanoethynyl)phenyl)butanamide | ||
|---|---|---|---|---|
| CAS Number | 1539292-61-9 | Molecular Weight | 227.26 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C13H13N3O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of 4-amino-N-(4-(2-cyanoethynyl)phenyl)butanamideAPN-NH2 is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
| Name | APN-NH2 |
|---|
| Description | APN-NH2 is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
|---|---|
| Related Catalog | |
| Target |
Alkyl-Chain |
| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
| References |
| Molecular Formula | C13H13N3O |
|---|---|
| Molecular Weight | 227.26 |
| InChIKey | RLTVJTXRTMTNBC-UHFFFAOYSA-N |
| SMILES | N#CC#Cc1ccc(NC(=O)CCCN)cc1 |