ML355
Modify Date: 2024-01-07 19:21:18
ML355 structure
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Common Name | ML355 | ||
|---|---|---|---|---|
| CAS Number | 1532593-30-8 | Molecular Weight | 441.523 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 654.5±65.0 °C at 760 mmHg | |
| Molecular Formula | C21H19N3O4S2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 349.6±34.3 °C | |
Use of ML355ML355 is a potent and selective inhibitors of 12-Lipoxygenase(12-LOX) with IC50 of 0.34 μM, excellent selectivity over related lipoxygenases and cyclooxygenases, and possess favorable ADME properties.IC50 value: 0.34 μM [1]Target: 12-LOXML355 inhibits PAR-4 induced aggregation and calcium mobilization in human platelets and reduce 12-HETE in β-cells. |
| Name | ML355 |
|---|---|
| Synonym | More Synonyms |
| Description | ML355 is a potent and selective inhibitors of 12-Lipoxygenase(12-LOX) with IC50 of 0.34 μM, excellent selectivity over related lipoxygenases and cyclooxygenases, and possess favorable ADME properties.IC50 value: 0.34 μM [1]Target: 12-LOXML355 inhibits PAR-4 induced aggregation and calcium mobilization in human platelets and reduce 12-HETE in β-cells. |
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| Related Catalog | |
| References |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 654.5±65.0 °C at 760 mmHg |
| Molecular Formula | C21H19N3O4S2 |
| Molecular Weight | 441.523 |
| Flash Point | 349.6±34.3 °C |
| Exact Mass | 441.081696 |
| LogP | 3.95 |
| Vapour Pressure | 0.0±2.0 mmHg at 25°C |
| Index of Refraction | 1.725 |
| Storage condition | 2-8℃ |
| ML355 |
| N-(1,3-Benzothiazol-2-yl)-4-[(2-hydroxy-3-methoxybenzyl)amino]benzenesulfonamide |
| Benzenesulfonamide, N-2-benzothiazolyl-4-[[(2-hydroxy-3-methoxyphenyl)methyl]amino]- |