Z-Ala-Ala-Asn-AMC

Modify Date: 2025-08-27 20:11:15

Z-Ala-Ala-Asn-AMC structure	Common Name	Z-Ala-Ala-Asn-AMC
	CAS Number	149697-16-5	Molecular Weight	565.57400
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₈H₃₀N₄O₉	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Z-Ala-Ala-Asn-AMC

Z-Ala-Ala-Asn-AMC (Cbz-Ala-Ala-Asn-AMC) is the legumain substrate. Overexpressed legumain in 293 HEK-Leg cells potently cleaved CBZ-Ala-Ala-Asn-AMC[1].

Name	z-ala-ala-asn-amc
Synonym	More Synonyms

Description	Z-Ala-Ala-Asn-AMC (Cbz-Ala-Ala-Asn-AMC) is the legumain substrate. Overexpressed legumain in 293 HEK-Leg cells potently cleaved CBZ-Ala-Ala-Asn-AMC[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
In Vitro	The first legumain fluorogenic substrate Cbz-Ala-Ala-Asn-AMC based on the P3-P2-P1 sequence Ala-Ala-Asn. The synthetic substrate Cbz-Ala-Ala-Asn-AMC is effectively cleaved by S. mansoni legumain and human legumain with Kms of 90 and 80 uM respectively[2][3].
References	[1]. Stern L, Perry R, Ofek P, Many A, Shabat D, Satchi-Fainaro R. A novel antitumor prodrug platform designed to be cleaved by the endoprotease legumain. Bioconjug Chem. 2009;20(3):500-510. [2]. James C. Powers, et al. Propenoyl hydrazides. US7482379B2. [3]. Poreba M, et al. Counter Selection Substrate Library Strategy for Developing Specific Protease Substrates and Probes. Cell Chem Biol. 2016;23(8):1023-1035.

Molecular Formula	C₂₈H₃₀N₄O₉
Molecular Weight	565.57400
Exact Mass	565.21700
PSA	198.93000
LogP	3.16570

z-ala-ala-asn-mca

benzyloxycarbonyl-l-alanyl-l-alanyl-l-asparagine 4-methylcoumaryl-7-amide

z-aan-amc

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Z-Ala-Ala-Asn-AMC
Price: Check
Purity: 99.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

DC Chemicals Limited
China
Product Name: Z-Ala-Ala-Asn-AMC
Price: $Inquiry/250mg $Inquiry/100mg $Inquiry/1g
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

Get all suppliers and price by the below link:

Z-Ala-Ala-Asn-AMC suppliers

Price: ￥1400/1 mg

Reference only. check more Z-Ala-Ala-Asn-AMC price

Z-Ala-Ala-Asn-AMC

Use of Z-Ala-Ala-Asn-AMC

Names

Z-Ala-Ala-Asn-AMC Biological Activity

Chemical & Physical Properties

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.