Procaspase-IN-5

Modify Date: 2025-08-26 21:41:41

Procaspase-IN-5 Structure
Procaspase-IN-5 structure
Common Name Procaspase-IN-5
CAS Number 1489285-17-7 Molecular Weight 388.48
Density N/A Boiling Point N/A
Molecular Formula C17H12N2O3S3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Procaspase-IN-5


Procaspase-IN-5 is a human DNA polymerase λ inhibitor. Procaspase-IN-5 has DNA polymerization function and TdT function with an IC50 value of 5.9 μM and 4.5 μM, respectively. Procaspase-IN-5 can be used for the research of cancer[1].

 Names

Name Procaspase-IN-5

 Procaspase-IN-5 Biological Activity

Description Procaspase-IN-5 is a human DNA polymerase λ inhibitor. Procaspase-IN-5 has DNA polymerization function and TdT function with an IC50 value of 5.9 μM and 4.5 μM, respectively. Procaspase-IN-5 can be used for the research of cancer[1].
Related Catalog
Target

IC50: 5.9 μM (DNA polymerization function); 4.5 μM (TdT function)[1].

References

[1]. Strittmatter T, et al. Expanding the scope of human DNA polymerase λ and β inhibitors. ACS Chem Biol. 2014 Jan 17;9(1):282-90.  

 Chemical & Physical Properties

Molecular Formula C17H12N2O3S3
Molecular Weight 388.48
InChIKey SHKDXDWJERWCHI-DHDCSXOGSA-N
SMILES Cc1ccccc1Sc1ccc(C=C2SC(=S)NC2=O)cc1[N+](=O)[O-]
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