Me-triacetyl-β-D-glucopyranuronate-Ph-ald-NO2 structure
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Common Name | Me-triacetyl-β-D-glucopyranuronate-Ph-ald-NO2 | ||
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| CAS Number | 148579-93-5 | Molecular Weight | 483.380 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 582.6±50.0 °C at 760 mmHg | |
| Molecular Formula | C20H21NO13 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 219.6±32.1 °C | |
Use of Me-triacetyl-β-D-glucopyranuronate-Ph-ald-NO2Me-triacetyl-β-D-glucopyranuronate-Ph-ald-NO2 is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
| Name | 4-Formyl-2-nitrophenyl methyl 2,3,4-tri-O-acetyl-β-D-glucopyranosiduronate |
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| Synonym | More Synonyms |
| Description | Me-triacetyl-β-D-glucopyranuronate-Ph-ald-NO2 is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). |
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| Related Catalog | |
| Target |
Cleavable |
| In Vitro | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |
| References |
[1]. Benatuil, Lorenzo, et al. Anti-B7-H3 antibodies and antibody drug conjugates. WO2017214339. |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 582.6±50.0 °C at 760 mmHg |
| Molecular Formula | C20H21NO13 |
| Molecular Weight | 483.380 |
| Flash Point | 219.6±32.1 °C |
| Exact Mass | 483.101288 |
| LogP | 2.62 |
| Vapour Pressure | 0.0±1.6 mmHg at 25°C |
| Index of Refraction | 1.550 |
| InChIKey | MHAQOFAFDHVKQE-KVIJGQROSA-N |
| SMILES | COC(=O)C1OC(Oc2ccc(C=O)cc2[N+](=O)[O-])C(OC(C)=O)C(OC(C)=O)C1OC(C)=O |
| 4-Formyl-2-nitrophenyl methyl 2,3,4-tri-O-acetyl-β-D-glucopyranosiduronate |
| Benzaldehyde, 3-nitro-4-[(2,3,4-tri-O-acetyl-6-methyl-β-D-glucopyranuronosyl)oxy]- |