Metyltetraprole

Modify Date: 2025-08-25 17:03:18

Metyltetraprole Structure
Metyltetraprole structure
Common Name Metyltetraprole
CAS Number 1472649-01-6 Molecular Weight 396.83
Density N/A Boiling Point N/A
Molecular Formula C19H17ClN6O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Metyltetraprole


Metyltetraprole is a promising fungicide with EC50 values of both 0.002 ppm against sensitive wild-type and G143A mutant of Zymoseptoria tritici. Metyltetraprole is effective against QoI (quinone outside inhibitor) resistant strains. Metyltetraprole inhibits the respiratory chain via complex III[1][2].

 Names

Name Metyltetraprole

 Metyltetraprole Biological Activity

Description Metyltetraprole is a promising fungicide with EC50 values of both 0.002 ppm against sensitive wild-type and G143A mutant of Zymoseptoria tritici. Metyltetraprole is effective against QoI (quinone outside inhibitor) resistant strains. Metyltetraprole inhibits the respiratory chain via complex III[1][2].
Related Catalog
References

[1]. Matsuzaki Y, et al. Discovery of metyltetraprole: Identification of tetrazolinone pharmacophore to overcome QoI resistance. Bioorg Med Chem. 2020 Jan 1;28(1):115211.

[2]. Suemoto H, et al. Metyltetraprole, a novel putative complex III inhibitor, targets known QoI-resistant strains of Zymoseptoria tritici and Pyrenophora teres. Pest Manag Sci. 2019 Apr;75(4):1181-1189.

 Chemical & Physical Properties

Molecular Formula C19H17ClN6O2
Molecular Weight 396.83
InChIKey XUQQRGKFXLAPNV-UHFFFAOYSA-N
SMILES Cc1cccc(-n2nnn(C)c2=O)c1COc1ccn(-c2ccc(Cl)cc2)n1
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