Metyltetraprole

Modify Date: 2024-01-02 22:39:27

Metyltetraprole structure	Common Name	Metyltetraprole
	CAS Number	1472649-01-6	Molecular Weight	396.83
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₉H₁₇ClN₆O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Metyltetraprole

Metyltetraprole is a promising fungicide with EC50 values of both 0.002 ppm against sensitive wild-type and G143A mutant of Zymoseptoria tritici. Metyltetraprole is effective against QoI (quinone outside inhibitor) resistant strains. Metyltetraprole inhibits the respiratory chain via complex III[1][2].

Name	Metyltetraprole

Description	Metyltetraprole is a promising fungicide with EC50 values of both 0.002 ppm against sensitive wild-type and G143A mutant of Zymoseptoria tritici. Metyltetraprole is effective against QoI (quinone outside inhibitor) resistant strains. Metyltetraprole inhibits the respiratory chain via complex III[1][2].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Fungal
References	[1]. Matsuzaki Y, et al. Discovery of metyltetraprole: Identification of tetrazolinone pharmacophore to overcome QoI resistance. Bioorg Med Chem. 2020 Jan 1;28(1):115211. [2]. Suemoto H, et al. Metyltetraprole, a novel putative complex III inhibitor, targets known QoI-resistant strains of Zymoseptoria tritici and Pyrenophora teres. Pest Manag Sci. 2019 Apr;75(4):1181-1189.

Description

Related Catalog

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Fungal

References

[1]. Matsuzaki Y, et al. Discovery of metyltetraprole: Identification of tetrazolinone pharmacophore to overcome QoI resistance. Bioorg Med Chem. 2020 Jan 1;28(1):115211.

[2]. Suemoto H, et al. Metyltetraprole, a novel putative complex III inhibitor, targets known QoI-resistant strains of Zymoseptoria tritici and Pyrenophora teres. Pest Manag Sci. 2019 Apr;75(4):1181-1189.