Alcaftadine
Modify Date: 2025-08-25 02:12:21
Alcaftadine structure
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Common Name | Alcaftadine | ||
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| CAS Number | 147084-10-4 | Molecular Weight | 307.389 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 556.2±60.0 °C at 760 mmHg | |
| Molecular Formula | C19H21N3O | Melting Point | 167 °C | |
| MSDS | N/A | Flash Point | 290.2±32.9 °C | |
Use of AlcaftadineAlcaftadine(R89674) is a H1 histamine receptor antagonist, which is used to prevent eye irritation brought on by allergic conjunctivitis.Target: H1 Histamine ReceptorAlcaftadine is a broad-spectrum antihistamine displaying a high affinity for histamine H1 and H2 receptors and a lower affinity for H4 receptors. alcaftadine was more effective than placebo and at least as effective as olopatadine 0.01% in preventing ocular itching at 15 minutes and at 16 hours after administration. Alcaftadine 0.025% ophthalmic solution has been approved by the U.S. Food and Drug Administration for prevention of itching associated with allergic conjunctivitis in patients over 2 years of age [1]. Alcaftadine is a safe and effective option for the prevention of ocular itching associated with allergic conjunctivitis, is dosed once daily, and is competitively priced among prescription medications for allergic conjunctivitis [2]. |
| Name | alcaftadine |
|---|---|
| Synonym | More Synonyms |
| Description | Alcaftadine(R89674) is a H1 histamine receptor antagonist, which is used to prevent eye irritation brought on by allergic conjunctivitis.Target: H1 Histamine ReceptorAlcaftadine is a broad-spectrum antihistamine displaying a high affinity for histamine H1 and H2 receptors and a lower affinity for H4 receptors. alcaftadine was more effective than placebo and at least as effective as olopatadine 0.01% in preventing ocular itching at 15 minutes and at 16 hours after administration. Alcaftadine 0.025% ophthalmic solution has been approved by the U.S. Food and Drug Administration for prevention of itching associated with allergic conjunctivitis in patients over 2 years of age [1]. Alcaftadine is a safe and effective option for the prevention of ocular itching associated with allergic conjunctivitis, is dosed once daily, and is competitively priced among prescription medications for allergic conjunctivitis [2]. |
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| Related Catalog | |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 556.2±60.0 °C at 760 mmHg |
| Melting Point | 167 °C |
| Molecular Formula | C19H21N3O |
| Molecular Weight | 307.389 |
| Flash Point | 290.2±32.9 °C |
| Exact Mass | 307.168457 |
| PSA | 38.13000 |
| LogP | 3.20 |
| Vapour Pressure | 0.0±1.5 mmHg at 25°C |
| Index of Refraction | 1.663 |
| InChIKey | MWTBKTRZPHJQLH-UHFFFAOYSA-N |
| SMILES | CN1CCC(=C2c3ccccc3CCn3c(C=O)cnc32)CC1 |
| Lastacaft |
| 11-(1-methylpiperidin-4-ylidene)-5,6-dihydroimidazo[2,1-b][3]benzazepine-3-carbaldehyde |
| alcaftadina |
| alcaftadinum |
| 11-(1-Methyl-4-piperidinylidene)-6,11-dihydro-5H-imidazo[2,1-b][3]benzazepine-3-carbaldehyde |
| UNII-7Z8O94ECSX |
| 5H-Imidazo[2,1-b][3]benzazepine-3-carboxaldehyde, 6,11-dihydro-11-(1-methyl-4-piperidinylidene)- |
| Vilasta |
| Alcaftadine |