Formamide,N-methyl-N-[(7S)-5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl]-

Modify Date: 2025-09-09 10:16:54

Formamide,N-methyl-N-[(7S)-5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl]- structure	Common Name	Formamide,N-methyl-N-[(7S)-5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl]-
	CAS Number	14686-61-4	Molecular Weight	399.43700
	Density	1.25g/cm3	Boiling Point	705.1ºC at 760 mmHg
	Molecular Formula	C₂₂H₂₅NO₆	Melting Point	N/A
	MSDS	N/A	Flash Point	380.2ºC

Name	N-methyl-N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]formamide
Synonym	More Synonyms

Density	1.25g/cm3
Boiling Point	705.1ºC at 760 mmHg
Molecular Formula	C₂₂H₂₅NO₆
Molecular Weight	399.43700
Flash Point	380.2ºC
Exact Mass	399.16800
PSA	74.30000
LogP	3.45960
Vapour Pressure	9.98E-20mmHg at 25°C
Index of Refraction	1.59

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GH0795000

CHEMICAL NAME :: Colchicine, N-deacetyl-N-formyl-N-methyl-

CAS REGISTRY NUMBER :: 14686-61-4

BEILSTEIN REFERENCE NO. :: 3179104

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C22-H25-N-O6

MOLECULAR WEIGHT :: 399.48

WISWESSER LINE NOTATION :: L B677 MV&T&J CO1 DO1 EO1 JN1&VH NO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intramuscular

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 72 mg/kg

TOXIC EFFECTS :: Nutritional and Gross Metabolic - weight loss or decreased weight gain

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 24,257,1981

(-)-Demecolcine

CAS#:477-30-5

Ethyl formate

CAS#:109-94-4

~78%

Formamide,N-met...

CAS#:14686-61-4

Literature: Dumont; Brossi; Silverton Journal of Organic Chemistry, 1986 , vol. 51, # 13 p. 2515 - 2521

Precursor 2
CAS#:477-30-5 (-)-Demecolcine CAS#:109-94-4 Ethyl formate
DownStream 1
CAS#:477-30-5 (-)-Demecolcine

N-Methyl-N-((S)-1,2,3,10-tetramethoxy-9-oxo-5,6,7,9-tetrahydro-benzo[a]heptalen-7-yl)-formamid

Formamide,N-methyl-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo(a)heptalen-7-yl)

(-)-N-formyldemecolcine

N-methyl-N-((S)-1,2,3,10-tetramethoxy-9-oxo-5,6,7,9-tetrahydro-benzo[a]heptalen-7-yl)-formamide

COLCHICINE,N-DEACETYL-N-FORMYL-N-METHYL

N-Formyldemeocolcine

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Formamide,N-methyl-N-[(7S)-5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl]-

Names

Chemical & Physical Properties

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

Synthetic Route

Precursor & DownStream

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.