C8 dihydro Ceramide (d18:0/8:0)

Modify Date: 2025-08-24 18:13:02

C8 dihydro Ceramide (d18:0/8:0) structure	Common Name	C8 dihydro Ceramide (d18:0/8:0)
	CAS Number	145774-33-0	Molecular Weight	427.70400
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₆H₅₃NO₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of C8 dihydro Ceramide (d18:0/8:0)

C8 Dihydroceramide is a negative control of C8 Ceramide. C8-Ceramide (N-Octanoyl-D-erythro-sphingosine) is a cell-permeable analog of naturally occurring ceramides. C8-Ceramide has anti-proliferation properties and acts as a potent chemotherapeutic agent. C8-Ceramide stimulates dendritic cells to promote T cell responses upon virus infections. C8-Ceramide induces slight activation of protein kinase (PKC) in vitro[1][2][3][4].

Name	N-[(2S,3R)-1,3-dihydroxyoctadecan-2-yl]octanamide
Synonym	More Synonyms

Description	C8 Dihydroceramide is a negative control of C8 Ceramide. C8-Ceramide (N-Octanoyl-D-erythro-sphingosine) is a cell-permeable analog of naturally occurring ceramides. C8-Ceramide has anti-proliferation properties and acts as a potent chemotherapeutic agent. C8-Ceramide stimulates dendritic cells to promote T cell responses upon virus infections. C8-Ceramide induces slight activation of protein kinase (PKC) in vitro[1][2][3][4].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
In Vitro	C8-dihydro-ceramide had no effect on cell viability in any of the cell lines tested[5].
References	[1]. Rebeca López-Marure , et al. Ceramide promotes the death of human cervical tumor cells in the absence of biochemical and morphological markers of apoptosis. Biochem Biophys Res Commun. 2002 May 10;293(3):1028-36. [2]. Yuli C. Chang, et al. Exogenous C8-Ceramide Induces Apoptosis by Overproduction of ROS and the Switch of Superoxide Dismutases SOD1 to SOD2 in Human Lung Cancer Cells. Int J Mol Sci. 2018 Oct; 19(10): 3010. [3]. H W Huang, et al. Ceramides modulate protein kinase C activity and perturb the structure of Phosphatidylcholine/Phosphatidylserine bilayers. Biophys J. 1999 Sep; 77(3): 1489-1497. [4]. Lan Weiss, et al. Ceramide contributes to pathogenesis and may be targeted for therapy in VCP inclusion body myopathy. Hum Mol Genet. 2021 Jan 7;ddaa248. [5]. Rebeca López-Marure, et al. Ceramide promotes the death of human cervical tumor cells in the absence of biochemical and morphological markers of apoptosis. Biochem Biophys Res Commun. 2002 May 10;293(3):1028-36.

Molecular Formula	C₂₆H₅₃NO₃
Molecular Weight	427.70400
Exact Mass	427.40300
PSA	73.05000
LogP	7.50650
Storage condition	-20°C

C8 dihydrosphingosine

N-08:0 Sphinganine C8 Sphinganine C8 dihydrosphingosine N-(octanoyl)-sphinganine

N-08:0 Sphinganine

C8 DIHYDROCERAMIDE

C8 Sphinganine

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C8 dihydro Ceramide (d18:0/8:0)

Use of C8 dihydro Ceramide (d18:0/8:0)

Names

C8 dihydro Ceramide (d18:0/8:0) Biological Activity

Chemical & Physical Properties

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.