Phosphatidylserines (bovine)

Modify Date: 2024-01-09 22:56:17

Phosphatidylserines (bovine) structure	Common Name	Phosphatidylserines (bovine)
	CAS Number	1446756-47-3	Molecular Weight	792.075
	Density	1.0±0.1 g/cm3	Boiling Point	816.3±75.0 °C at 760 mmHg
	Molecular Formula	C₄₂H₈₂NO₁₀P	Melting Point	N/A
	MSDS	N/A	Flash Point	447.5±37.1 °C

Use of Phosphatidylserines (bovine)

Phosphatidylserine is a conserved anti-inflammatory and immunosuppressive signal that is highly dysregulated in the tumor microenvironment and autoimmune diseases. During apoptosis and cellular stress，the related disrupting enzymes Xkr8 and TMEM16 mediate Phosphatidylserine externalization. Phosphatidylserine externalization produces a "eat me" signal that initiates endocytosis and helps clear the body of apoptotic cells. When pathogens use Phosphatidylserine and apoptotic mimicry to evade host immune responses，targeting Phosphatidylserine strategies can stimulate immune activity[1].

Name	Phosphatidylserines (bovine)
Synonym	More Synonyms

Description	Phosphatidylserine is a conserved anti-inflammatory and immunosuppressive signal that is highly dysregulated in the tumor microenvironment and autoimmune diseases. During apoptosis and cellular stress，the related disrupting enzymes Xkr8 and TMEM16 mediate Phosphatidylserine externalization. Phosphatidylserine externalization produces a "eat me" signal that initiates endocytosis and helps clear the body of apoptotic cells. When pathogens use Phosphatidylserine and apoptotic mimicry to evade host immune responses，targeting Phosphatidylserine strategies can stimulate immune activity[1].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Inflammation/Immunology
References	[1]. Birge RB, Boeltz S, Kumar S, Carlson J, Wanderley J, Calianese D, Barcinski M, Brekken RA, Huang X, Hutchins JT, Freimark B, Empig C, Mercer J, Schroit AJ, Schett G, Herrmann M. Phosphatidylserine is a global immunosuppressive signal in efferocytosis, infectious disease, and cancer. Cell Death Differ. 2016 Jun;23(6):962-78.

Density	1.0±0.1 g/cm3
Boiling Point	816.3±75.0 °C at 760 mmHg
Molecular Formula	C₄₂H₈₂NO₁₀P
Molecular Weight	792.075
Flash Point	447.5±37.1 °C
Exact Mass	791.567627
LogP	16.13
Vapour Pressure	0.0±6.3 mmHg at 25°C
Index of Refraction	1.481

Octadecanoic acid, (1R)-1-[[[[(2S)-2-amino-2-carboxyethoxy]hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl ester

1,2-distearoyl-sn-glycero-3-phosphoserine

O-{[(2R)-2,3-Bis(stearoyloxy)propoxy](hydroxy)phosphoryl}-L-serine

MFCD00135635

Phosphatidylserine

Phosphatidylserines (bovine)

Use of Phosphatidylserines (bovine)

Names

Phosphatidylserines (bovine) Biological Activity

Chemical & Physical Properties

Synonyms