Abacavir hydroxyacetate
Modify Date: 2025-08-26 19:44:55
Abacavir hydroxyacetate structure
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Common Name | Abacavir hydroxyacetate | ||
|---|---|---|---|---|
| CAS Number | 1446418-48-9 | Molecular Weight | 344.36800 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C16H20N6O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Abacavir hydroxyacetateAbacavir hydroxyacetate is an orally active inhibitor of IL-20 and PRINS. Abacavir hydroxyacetate reduces proliferation rate of skin in psoriasis as an immune modulator. Abacavir hydroxyacetate can be used for the research of inflammatory skin problems[1][2]. |
| Name | [(1S,4R)-4-[2-amino-6-(cyclopropylamino)purin-9-yl]cyclopent-2-en-1-yl]methyl 2-hydroxyacetate |
|---|---|
| Synonym | More Synonyms |
| Description | Abacavir hydroxyacetate is an orally active inhibitor of IL-20 and PRINS. Abacavir hydroxyacetate reduces proliferation rate of skin in psoriasis as an immune modulator. Abacavir hydroxyacetate can be used for the research of inflammatory skin problems[1][2]. |
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| Related Catalog | |
| In Vivo | Abacavir hydroxyacetate (10-20 mg/kg; p.o. once) effectively controls psoriasis of mice[2]. Animal Model: 6 to 8-week-old male and female SCID mice with implantation of psoriatic tissue[2] Dosage: 10 and 20 mg/kg Administration: Oral gavage; 10-20 mg/kg once Result: Decreased the concentration of PRINS and 1L-20, and reduced the lesion area of skin. Showed a better effect than methotrexate in controlling psoriasis. |
| References |
| Molecular Formula | C16H20N6O3 |
|---|---|
| Molecular Weight | 344.36800 |
| Exact Mass | 344.16000 |
| PSA | 128.91000 |
| LogP | 0.63860 |
| InChIKey | ZBBZROWQLKCFQK-KOLCDFICSA-N |
| SMILES | Nc1nc(NC2CC2)c2ncn(C3C=CC(COC(=O)CO)C3)c2n1 |
| Abacavir hydroxyacetate |
| Prurisol |
| UNII-B3C7MG354B |
| Acetic acid,2-hydroxy-,((1S,4R)-4-(2-amino-6-(cyclopropylamino)-9H-purin-9-yl)-2-cyclopenten-1-yl)methyl ester |