Dofetilide N-oxide

Modify Date: 2025-08-27 16:12:32

Dofetilide N-oxide structure	Common Name	Dofetilide N-oxide
	CAS Number	144449-71-8	Molecular Weight	457.56400
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₉H₂₇N₃O₆S₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Dofetilide N-oxide

Dofetilide N-oxide (UK-116856) is a metabolite of Dofetilide. Dofetilide is a class III antiarrhythmic agent that blocks potassium channels[1][2].

Name	Dofetilide N-oxide
Synonym	More Synonyms

Description	Dofetilide N-oxide (UK-116856) is a metabolite of Dofetilide. Dofetilide is a class III antiarrhythmic agent that blocks potassium channels[1][2].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> Membrane Transporter/Ion Channel >> Potassium Channel
Target	Potassium channels[1][2]
References	[1]. Maisch B, et al. Pregnancy and cardiomyopathies. Herz. 2003 May;28(3):196-208. [2]. Snyders, D.J. and A. Chaudhary, High affinity open channel block by dofetilide of HERG expressed in a human cell line. Mol Pharmacol, 1996. 49(6): p. 949-55.

N-[4-(2-{[2-(4-methanesulfonylamino-phenyl)-ethyl]-methyl-amino}-ethoxy)-phenyl]-methanesulfonamide N-oxide

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