permafloxacin

Modify Date: 2025-08-25 16:31:36

permafloxacin structure	Common Name	permafloxacin
	CAS Number	143383-65-7	Molecular Weight	403.44700
	Density	1.354g/cm3	Boiling Point	601.3ºC at 760mmHg
	Molecular Formula	C₂₁H₂₆FN₃O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	317.4ºC

Name	1-cyclopropyl-6-fluoro-8-methoxy-7-[(3R)-3-[(1S)-1-(methylamino)ethyl]pyrrolidin-1-yl]-4-oxoquinoline-3-carboxylic acid
Synonym	More Synonyms

Density	1.354g/cm3
Boiling Point	601.3ºC at 760mmHg
Molecular Formula	C₂₁H₂₆FN₃O₄
Molecular Weight	403.44700
Flash Point	317.4ºC
Exact Mass	403.19100
PSA	83.80000
LogP	3.07240
Vapour Pressure	2.63E-15mmHg at 25°C
Index of Refraction	1.615

3R,1S-1-cyclopropyl-6-fluoro-7-[3-(1-N-tertbutoxycarbonyl-N-methylaminoethyl)-1-pyrrolidinyl]-8-methoxy-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid structure

3R,1S-1-cyclopr...

CAS#:143409-01-2

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permafloxacin Structure

permafloxacin

CAS#:143383-65-7

Literature: Murphy, Sean T.; Case, Heather L.; Ellsworth, Edmund; Hagen, Susan; Huband, Michael; Joannides, Themis; Limberakis, Chris; Marotti, Keith R.; Ottolini, Amy M.; Rauckhorst, Mark; Starr, Jeremy; Stier, Michael; Taylor, Clarke; Zhu, Tong; Blaser, Adrian; Denny, William A.; Lu, Guo-Liang; Smaill, Jeff B.; Rivault, Freddy Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 8 p. 2150 - 2155

tert-butyl ((S)-1-((R)-1-(1-cyclopropyl-3-(((difluoroboranyl)oxy)carbonyl)-6-fluoro-8-methoxy-4-oxo-1,4-dihydroquinolin-7-yl)pyrrolidin-3-yl)ethyl)(methyl)carbamate structure

tert-butyl ((S)...

CAS#:143409-16-9

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permafloxacin Structure

permafloxacin

CAS#:143383-65-7

Literature: Murphy, Sean T.; Case, Heather L.; Ellsworth, Edmund; Hagen, Susan; Huband, Michael; Joannides, Themis; Limberakis, Chris; Marotti, Keith R.; Ottolini, Amy M.; Rauckhorst, Mark; Starr, Jeremy; Stier, Michael; Taylor, Clarke; Zhu, Tong; Blaser, Adrian; Denny, William A.; Lu, Guo-Liang; Smaill, Jeff B.; Rivault, Freddy Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 8 p. 2150 - 2155

1,1-dimethylethyl [S-(R*,S*)]-methyl[1-(3-pyrrolidinyl)ethyl]carbamate structure

1,1-dimethyleth...

CAS#:143408-75-7

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permafloxacin Structure

permafloxacin

CAS#:143383-65-7

Literature: Murphy, Sean T.; Case, Heather L.; Ellsworth, Edmund; Hagen, Susan; Huband, Michael; Joannides, Themis; Limberakis, Chris; Marotti, Keith R.; Ottolini, Amy M.; Rauckhorst, Mark; Starr, Jeremy; Stier, Michael; Taylor, Clarke; Zhu, Tong; Blaser, Adrian; Denny, William A.; Lu, Guo-Liang; Smaill, Jeff B.; Rivault, Freddy Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 8 p. 2150 - 2155

[1-cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-(oxo-κO)-3-quinoline-carboxylato-κO3]difluoroboron structure

[1-cyclopropyl-...

CAS#:847233-56-1

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permafloxacin Structure

permafloxacin

CAS#:143383-65-7

Literature: Murphy, Sean T.; Case, Heather L.; Ellsworth, Edmund; Hagen, Susan; Huband, Michael; Joannides, Themis; Limberakis, Chris; Marotti, Keith R.; Ottolini, Amy M.; Rauckhorst, Mark; Starr, Jeremy; Stier, Michael; Taylor, Clarke; Zhu, Tong; Blaser, Adrian; Denny, William A.; Lu, Guo-Liang; Smaill, Jeff B.; Rivault, Freddy Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 8 p. 2150 - 2155

Precursor 2
CAS#:143408-75-7 1,1-dimethyleth... CAS#:847233-56-1 [1-cyclopropyl-...
DownStream 0

1-cyclopropyl-6-fluoro-8-methoxy-7-[3-(1-methylamino-ethyl)-pyrrolidin-1-yl]-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid

Premafloxacin (USAN/INN)

Premafloxacin

JB-1

UNII-UOM2HMO524

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