ODM-203

Modify Date: 2024-04-05 08:06:18

ODM-203 structure	Common Name	ODM-203
	CAS Number	1430723-35-5	Molecular Weight	505.54
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₆H₂₁F₂N₅O₂S	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of ODM-203

ODM-203 is a potent FGFR and VEGFR families inhibitor with IC50s of 11, 16, 6, 35 nM towards recombinant FGFR1, FGFR2, FGFR3 and FGFR4 as well as 26, 9, 5 nM towards VEGFR1, VEGFR2 and VEGFR3, respectively. ODM-203 exhibits strong anti-tumor activity and induces anti-tumor immunity[1].

Name	ODM-203

Description	ODM-203 is a potent FGFR and VEGFR families inhibitor with IC50s of 11, 16, 6, 35 nM towards recombinant FGFR1, FGFR2, FGFR3 and FGFR4 as well as 26, 9, 5 nM towards VEGFR1, VEGFR2 and VEGFR3, respectively. ODM-203 exhibits strong anti-tumor activity and induces anti-tumor immunity[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Protein Tyrosine Kinase/RTK >> FGFR Signaling Pathways >> Protein Tyrosine Kinase/RTK >> VEGFR
Target	FGFR1:11 nM (IC50) FGFR2:16 nM (IC50) FGFR3:6 nM (IC50) FGFR4:35 nM (IC50) VEGFR1:26 nM (IC50) VEGFR2:9 nM (IC50) VEGFR3:5 nM (IC50) DDR1:6 nM (IC50) RET:8 nM (IC50) SIK3:23 nM (IC50) PDGFRa:35 nM (IC50) MINK1:41 nM (IC50) MAP4K4:49 nM (IC50)
References	[1]. Holmström TH, et al. ODM-203, a Selective Inhibitor of FGFR and VEGFR, Shows Strong Antitumor Activity, and Induces Antitumor Immunity. Mol Cancer Ther. 2019 Jan;18(1):28-38.

Molecular Formula	C₂₆H₂₁F₂N₅O₂S
Molecular Weight	505.54

DC Chemicals Limited
China
Product Name: ODM-203
Price: $600.0/100mg $1000.0/250mg $1900.0/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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