1alpha-Hydroxy VD4

Modify Date: 2024-01-10 10:25:14

1alpha-Hydroxy VD4 Structure
1alpha-Hydroxy VD4 structure
 Common Name 1alpha-Hydroxy VD4
CAS Number 143032-85-3 Molecular Weight 414.66400
Density N/A Boiling Point N/A
Molecular Formula C28H46O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 1alpha-Hydroxy VD4


1alpha-Hydroxy VD4 , a 1alpha(OH)D derivative, can effectively induce the differentiation of monoblastic leukaemia U937, P39/TSU and P31/FUJ cells. IC50 value；Target: VD analog

 Names

Name (1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(2R,5S)-5,6-dimethylheptan-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-diol
Synonym More Synonyms

 1alpha-Hydroxy VD4 Biological Activity

Description 1alpha-Hydroxy VD4 , a 1alpha(OH)D derivative, can effectively induce the differentiation of monoblastic leukaemia U937, P39/TSU and P31/FUJ cells. IC50 value；Target: VD analog
Related Catalog
References

[1]. M Makishima, et al. Growth inhibition and differentiation induction in human monoblastic leukaemia cells by 1alpha-hydroxyvitamin D derivatives and their enhancement by combination with hydroxyurea. British Journal of Cancer (1998) 77, 33-39

 Chemical & Physical Properties

Molecular Formula C28H46O2
Molecular Weight 414.66400
Exact Mass 414.35000
PSA 40.46000
LogP 6.83580
Storage condition 2-8℃

 Synonyms

1alpha-Hydroxy VD4
CS-0805
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(1R,3S,5Z)-5-[(2E)-2-[(1R,3aS,7aR)-1-[(2R,5R)-5-ethyl-6-methylheptan-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-diol
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Chemsrc provides 1alpha-Hydroxy VD4(CAS#:143032-85-3) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of 1alpha-Hydroxy VD4 are included as well.>> amp version: 1alpha-Hydroxy VD4

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