Azt-pmap

Modify Date: 2025-08-27 12:42:44

Azt-pmap structure	Common Name	Azt-pmap
	CAS Number	142629-81-0	Molecular Weight	508.42200
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₀H₂₅N₆O₈P	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Azt-pmap

Azt-pmap, a nucleoside analogue, is an aryl phosphate derivative of AZT. Azt-pmap shows anti-HIV activity[1]. AZT is a nucleoside reverse transcriptase inhibitor (NRTI) for HIV infection[2].

Name	So221
Synonym	More Synonyms

Description	Azt-pmap, a nucleoside analogue, is an aryl phosphate derivative of AZT. Azt-pmap shows anti-HIV activity[1]. AZT is a nucleoside reverse transcriptase inhibitor (NRTI) for HIV infection[2].
Related Catalog	Signaling Pathways >> Anti-infection >> HIV Research Areas >> Infection
Target	HIV-1
In Vitro	Azt-pmap shows anti-HIV-1 activities in infected C8166 and JM cells with EC50s of 0.08 and0.32 μM, respectively. Azt-pmap displays toxicities in infected C8166 and JM cells with TC50s of 500 μM, respectively. Azt-pmap inhibits virus replication[1].
References	[1]. McGuigan C, et al. Aryl phosphate derivatives of AZT retain activity against HIV1 in cell lines which are resistant to the action of AZT. Antiviral Res. 1992 Apr;17(4):311-21. [2]. Gray LR, et al. The NRTIs lamivudine, stavudine and zidovudine have reduced HIV-1 inhibitory activity in astrocytes. PLoS One. 2013 Apr 16;8(4):e62196.

Molecular Formula	C₂₀H₂₅N₆O₈P
Molecular Weight	508.42200
Exact Mass	508.14700
PSA	197.51000
LogP	2.00986

(S)-2-{[(2S,3S,5R)-3-Azido-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-2-ylmethoxy]-phenoxy-phosphorylamino}-propionic acid methyl ester

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Azt-pmap
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 3'-azidothymidine-5'-(phenylmethoxyalanyl)phosphate
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.