Ezetimibe phenoxy glucuronide-D4

Modify Date: 2025-08-26 13:58:18

Ezetimibe phenoxy glucuronide-D4 Structure
Ezetimibe phenoxy glucuronide-D4 structure
Common Name Ezetimibe phenoxy glucuronide-D4
CAS Number 1426174-41-5 Molecular Weight 589.57
Density N/A Boiling Point N/A
Molecular Formula C30H25D4F2NO9 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Ezetimibe phenoxy glucuronide-D4


Ezetimibe phenoxy glucuronide-D4 (Ezetimibe glucuronide-D4) is the deuterium labeled Ezetimibe phenoxy glucuronide. Ezetimibe phenoxy glucuronide is the active metabolite of Ezetimibe. Antihyperlipoproteinemic activity[1]. Ezetimibe is a potent cholesterol absorption inhibitor[2].

 Names

Name Ezetimibe phenoxy glucuronide-D4

 Ezetimibe phenoxy glucuronide-D4 Biological Activity

Description Ezetimibe phenoxy glucuronide-D4 (Ezetimibe glucuronide-D4) is the deuterium labeled Ezetimibe phenoxy glucuronide. Ezetimibe phenoxy glucuronide is the active metabolite of Ezetimibe. Antihyperlipoproteinemic activity[1]. Ezetimibe is a potent cholesterol absorption inhibitor[2].
Related Catalog
In Vivo After oral administration, Ezetimibe is absorbed in the small intestine and more than 80% of Ezetimibe metabolized to Ezetimibe Glucuronide[1].
References

[1]. Stolk MF, et al. Severe hepatic side effects of ezetimibe. Clin Gastroenterol Hepatol. 2006 Jul;4(7):908-11.

[2]. Lee DH, et al. Ezetimibe, an NPC1L1 inhibitor, is a potent Nrf2 activator that protects mice from diet-induced nonalcoholic steatohepatitis. Free Radic Biol Med. 2016 Sep 12;99:520-532.

 Chemical & Physical Properties

Molecular Formula C30H25D4F2NO9
Molecular Weight 589.57
InChIKey UOFYCFMTERCNEW-MKSNJYNSSA-N
SMILES O=C(O)C1OC(Oc2ccc(C3C(CCC(O)c4ccc(F)cc4)C(=O)N3c3ccc(F)cc3)cc2)C(O)C(O)C1O
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