DFAME

Modify Date: 2025-08-25 10:36:53

DFAME Structure
DFAME structure
Common Name DFAME
CAS Number 1420815-55-9 Molecular Weight 322.26
Density N/A Boiling Point N/A
Molecular Formula C15H12F2N2O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Names

Name DFAME

 DFAME Biological Activity

Description DFAME 是一种红色荧光基团 (Ex=508 nm, Em=641 nm)。Beetroot 和 Corn 是二聚体荧光 RNA 适体,可与 DFAME 结合形成 Beetroot-DFAME 复合体(Kd=460nM) 和 Corn-DFAME 复合体 (Kd=3600nM)。Beetroot-DFAME 和 Corn-DFAME 可用于在细胞中形成 RNA 组装体。 RNA 结构具有自组装特性,可用于进行 RNA 纳米结构的研究。DNA/RNA 纳米结构将可用于细胞和基因疗法 (CGT) 的研究[1]。
Related Catalog
References

[1]. Wu J, et al. Self-Assembly of Intracellular Multivalent RNA Complexes Using Dimeric Corn and Beetroot Aptamers. J Am Chem Soc. 2022 Mar 30;144(12):5471-5477.

[2]. Jiahui Wu, et al. Self-Assembly of Intracellular Multivalent RNA Complexes Using Dimeric Corn and Beetroot Aptamers. J Am Chem Soc. 2022 Mar 30;144(12):5471-5477.

 Chemical & Physical Properties

Molecular Formula C15H12F2N2O4
Molecular Weight 322.26
InChIKey LXQQJPJEYBZZSO-KDYKCUIDSA-N
SMILES COC(=O)C=CC1=NC(=Cc2cc(F)c(O)c(F)c2)C(=O)N1C
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