AMG-333

Modify Date: 2025-11-26 20:17:51

AMG-333 structure	Common Name	AMG-333
	CAS Number	1416799-28-4	Molecular Weight	453.32
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₀H₁₂F₅N₃O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of AMG-333

AMG 333 is a potent and highly selective TRPM8 antagonist with an IC50 of 13 nM.

Name	AMG 333
Synonym	More Synonyms

Description	AMG 333 is a potent and highly selective TRPM8 antagonist with an IC50 of 13 nM.
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> TRP Channel Research Areas >> Cardiovascular Disease Research Areas >> Neurological Disease
Target	IC50: 13 nM (TRPM8)[1]
References	[1]. Horne DB, et al. Discovery of TRPM8 Antagonist ( S)-6-(((3-Fluoro-4-(trifluoromethoxy)phenyl)(3-fluoropyridin-2-yl)methyl)carbamoyl)nicotinic Acid (AMG 333), a Clinical Candidate for the Treatment of Migraine. J Med Chem. 2018 Sep 27;61(18):8186-8201.

Molecular Formula	C₂₀H₁₂F₅N₃O₄
Molecular Weight	453.32

Hazard Codes	Xi

MFCD31813692

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: AMG-333
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

ShangHai DC Chemicals Co.,Ltd
China
Product Name: AMG-333
Price: ￥Inquiry/1g
Purity: 98.9%
Delivery: 1 Day
Contact: Tony Lai
Email: order@dcchemicals.com

DC Chemicals Limited
China
Product Name: AMG-333
Price: $700.0/100mg $1200.0/250mg $2600.0/1g
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

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