(±)-BI-D
Modify Date: 2025-08-25 06:50:45
(±)-BI-D structure
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Common Name | (±)-BI-D | ||
|---|---|---|---|---|
| CAS Number | 1416258-16-6 | Molecular Weight | 405.486 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 587.3±50.0 °C at 760 mmHg | |
| Molecular Formula | C25H27NO4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 309.0±30.1 °C | |
Use of (±)-BI-D(±)-BI-D is a potent ALLINI(An allosteric IN inhibitor) that binds integrase at the LEDGF/p75 binding site.IC50 value: 2.4–2.9 μM(HIV-Luc infection of WT and Hdgfrp2 KO cells) [1]Target: integrase inhibitorin vitro: Approximately 2.4–2.9 μM of BI-D was required to inhibit 50% of HIV-Luc infection of WT and Hdgfrp2 KO cells, while the IC50 decreased dramatically, to 160–200 nM, in Psip1 and double-KO cells [1]. |
| Name | (±)-BI-D |
|---|---|
| Synonym | More Synonyms |
| Description | (±)-BI-D is a potent ALLINI(An allosteric IN inhibitor) that binds integrase at the LEDGF/p75 binding site.IC50 value: 2.4–2.9 μM(HIV-Luc infection of WT and Hdgfrp2 KO cells) [1]Target: integrase inhibitorin vitro: Approximately 2.4–2.9 μM of BI-D was required to inhibit 50% of HIV-Luc infection of WT and Hdgfrp2 KO cells, while the IC50 decreased dramatically, to 160–200 nM, in Psip1 and double-KO cells [1]. |
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| Related Catalog | |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 587.3±50.0 °C at 760 mmHg |
| Molecular Formula | C25H27NO4 |
| Molecular Weight | 405.486 |
| Flash Point | 309.0±30.1 °C |
| Exact Mass | 405.194000 |
| LogP | 5.28 |
| Vapour Pressure | 0.0±1.7 mmHg at 25°C |
| Index of Refraction | 1.610 |
| InChIKey | ZFERZAMPQIXCPM-UHFFFAOYSA-N |
| SMILES | Cc1nc2ccccc2c(-c2ccc3c(c2)CCCO3)c1C(OC(C)(C)C)C(=O)O |
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