Sarolaner
Modify Date: 2025-08-25 20:45:26
Sarolaner structure
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Common Name | Sarolaner | ||
|---|---|---|---|---|
| CAS Number | 1398609-39-6 | Molecular Weight | 581.36 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C23H18Cl2F4N2O5S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of SarolanerSarolaner (PF-6450567) is an orally active, broad-spectrum ectoparasiticide, has efficacy against fleas and ticks on dogs, with LC80 of 0.3 μg/mL against C. felis and an LC100 of 0.003 μg/mL against O. turicata[1]. |
| Name | 1-[6-[(5S)-5-(3,5-dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4H-1,2-oxazol-3-yl]spiro[1H-2-benzofuran-3,3'-azetidine]-1'-yl]-2-methylsulfonylethanone |
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| Synonym | More Synonyms |
| Description | Sarolaner (PF-6450567) is an orally active, broad-spectrum ectoparasiticide, has efficacy against fleas and ticks on dogs, with LC80 of 0.3 μg/mL against C. felis and an LC100 of 0.003 μg/mL against O. turicata[1]. |
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| Related Catalog | |
| Target |
LC80: 0.3μg/mL (C. felis)[1] LC100: 0.003 μg/mL (O. turicata)[1] |
| References |
| Molecular Formula | C23H18Cl2F4N2O5S |
|---|---|
| Molecular Weight | 581.36 |
| Exact Mass | 580.02500 |
| PSA | 93.65000 |
| LogP | 4.78130 |
| InChIKey | FLEFKKUZMDEUIP-QFIPXVFZSA-N |
| SMILES | CS(=O)(=O)CC(=O)N1CC2(C1)OCc1cc(C3=NOC(c4cc(Cl)c(F)c(Cl)c4)(C(F)(F)F)C3)ccc12 |
| Storage condition | 2-8℃ |
| Sarolaner [USAN] |
| 1-(5'-((5S)-5-(3,5-Dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)-3'-H-spiro(azetidine-3,1'-(2)benzofuran)-1-yl)-2-(methylsulfonyl)ethanone |
| Ethanone,1-(5'-((5S)-5-(3,5-dichloro-4-fluorophenyl)-4,5-dihydro-5-(trifluoromethyl)-3-isoxazolyl)spiro(azetidine-3,1'(3'H)-isobenzofuran)-1-yl)-2-(methylsulfonyl) |
| Sarolaner |