N-Desmethyl Sildenafil
Modify Date: 2025-09-01 13:30:07
N-Desmethyl Sildenafil structure
|
Common Name | N-Desmethyl Sildenafil | ||
|---|---|---|---|---|
| CAS Number | 139755-82-1 | Molecular Weight | 460.55 | |
| Density | 1.44g/cm3 | Boiling Point | 685.7ºC at 760 mmHg | |
| Molecular Formula | C21H28N6O4S | Melting Point | 158-160ºC | |
| MSDS | N/A | Flash Point | 368.5ºC | |
Use of N-Desmethyl SildenafilN-Desmethyl Sildenafil (Desmethylsildenafil) is a major metabolite of Sildenafil. Sildenafil is a potent phosphodiesterase type 5 (PDE5) inhibitor[1][2]. |
| Name | N-Desmethyl Sildenafil |
|---|---|
| Synonym | More Synonyms |
| Description | N-Desmethyl Sildenafil (Desmethylsildenafil) is a major metabolite of Sildenafil. Sildenafil is a potent phosphodiesterase type 5 (PDE5) inhibitor[1][2]. |
|---|---|
| Related Catalog | |
| In Vitro | N-Desmethyl Sildenafil increases the amplitude of electroretinogram (ERG) recorded from the dark-adapted isolated rat retina, most probably through the enhancement of the photoreceptor cell response[1]. The formation of N-Desmethyl Sildenafil is examined using CYP3A supersomes co-expressing human P450 oxidoreductase and cytochrome b5. N-Desmethyl Sildenafil is catalyzed by CYP3A4, CYP3A5, and to a lesser extent by CYP3A7[2]. |
| References |
| Density | 1.44g/cm3 |
|---|---|
| Boiling Point | 685.7ºC at 760 mmHg |
| Melting Point | 158-160ºC |
| Molecular Formula | C21H28N6O4S |
| Molecular Weight | 460.55 |
| Flash Point | 368.5ºC |
| Exact Mass | 460.18900 |
| PSA | 130.59000 |
| LogP | 2.61620 |
| Vapour Pressure | 1.17E-18mmHg at 25°C |
| Index of Refraction | 1.683 |
| 5-(2-ethoxy-5-piperazin-1-ylsulfonylphenyl)-1-methyl-3-propyl-4H-pyrazolo[4,3-d]pyrimidin-7-one |
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- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: N-Desmethyl Sildenafil
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- China
- Product Name: N-Desmethyl Sildenafil
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- Purity: 98.0%
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- Shanghai Amole Biotechnology Co., Ltd.
- China
- Product Name: N-Desmethyl Sildenafil
- Price: ￥Inquiry/10g ￥Inquiry/1g ￥Inquiry/250mg ￥Inquiry/5g
- Purity: 95.0%
- Delivery: Inquiry
- Contact: Xiyao Wang
- Email: 406104890@qq.com
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