CP-96486
Modify Date: 2025-09-08 17:33:40
CP-96486 structure
|
Common Name | CP-96486 | ||
|---|---|---|---|---|
| CAS Number | 139401-45-9 | Molecular Weight | 502.99 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C31H23ClN4O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of CP-96486CP-96486 is a potent and orally active leukotriene D4 (LTD4)/platelet activating factor (PAF) receptor antagonist with Kis of 20 and 24 nM, respectively. |
| Name | CP-96486 |
|---|
| Description | CP-96486 is a potent and orally active leukotriene D4 (LTD4)/platelet activating factor (PAF) receptor antagonist with Kis of 20 and 24 nM, respectively. |
|---|---|
| Related Catalog | |
| Target |
LTD4:20 nM (Ki) PAF receptor:24 nM (Ki) |
| In Vitro | CP-96486 (CP-96,486) antagonizes 3H-LTD4 binding to guinea pig lung membranes and 3H-PAF binding to rabbit platelets with Ki's of 20 and 24 nM respectively[1]. |
| In Vivo | CP-96486 (CP-96,486) inhibits iv LTD4- and iv PAF-induced bronchoconstriction in guinea pigs with ED50's of 0.27 and 0.26 mg/kg p.o. respectively[1]. |
| References |
| Molecular Formula | C31H23ClN4O |
|---|---|
| Molecular Weight | 502.99 |
| Storage condition | 2-8℃ |