G36
Modify Date: 2025-09-01 15:55:59
G36 structure
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Common Name | G36 | ||
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| CAS Number | 1392487-51-2 | Molecular Weight | 412.320 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 478.4±45.0 °C at 760 mmHg | |
| Molecular Formula | C22H22BrNO2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 243.1±28.7 °C | |
Use of G36G-36 is a cell permeable non-steroidal antagonist of G-protein-coupled estrogen receptor (GPER/GPR30) which selectively inhibits estrogen-mediated activation of PI3K by GPER, but not by ERα. G-36 also inhibits estrogen-mediated calcium mobilization (IC50=112 nM)[1]. |
| Name | (3aS,4R,9bR)-4-(6-Bromo-1,3-benzodioxol-5-yl)-8-isopropyl-3a,4,5, 9b-tetrahydro-3H-cyclopenta[c]quinoline |
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| Synonym | More Synonyms |
| Description | G-36 is a cell permeable non-steroidal antagonist of G-protein-coupled estrogen receptor (GPER/GPR30) which selectively inhibits estrogen-mediated activation of PI3K by GPER, but not by ERα. G-36 also inhibits estrogen-mediated calcium mobilization (IC50=112 nM)[1]. |
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| Related Catalog | |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 478.4±45.0 °C at 760 mmHg |
| Molecular Formula | C22H22BrNO2 |
| Molecular Weight | 412.320 |
| Flash Point | 243.1±28.7 °C |
| Exact Mass | 411.083374 |
| PSA | 30.49000 |
| LogP | 5.83 |
| Vapour Pressure | 0.0±1.2 mmHg at 25°C |
| Index of Refraction | 1.619 |
| InChIKey | QTOCPACSSHFGOY-ZCCHDVMBSA-N |
| SMILES | CC(C)c1ccc2c(c1)C1C=CCC1C(c1cc3c(cc1Br)OCO3)N2 |
| CaCCinh-A01 |
| (3aS,4R,9bR)-4-(6-Bromo-1,3-benzodioxol-5-yl)-8-isopropyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline |
| 3H-Cyclopenta[c]quinoline, 4-(6-bromo-1,3-benzodioxol-5-yl)-3a,4,5,9b-tetrahydro-8-(1-methylethyl)-, (3aS,4R,9bR)- |
| G-36 |