WAY-123398

Modify Date: 2025-08-25 16:50:18

Use of WAY-123398

WAY-123398 is a class III antiarrhythmic agent. WAY-123398 is a selective blocker of the delayed rectifier K+ current[1].

Name	4-(methanesulfonamido)-N-methyl-N-[2-[methyl-(1-methylbenzimidazol-2-yl)amino]ethyl]benzenesulfonamide
Synonym	More Synonyms

Description	WAY-123398 is a class III antiarrhythmic agent. WAY-123398 is a selective blocker of the delayed rectifier K+ current[1].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> Others >> Others
References	[1]. Spinelli W, et al. Cellular electrophysiology of WAY-123,398, a new class III antiarrhythmic agent: specificity of IK block and lack of reverse use dependence in cat ventricular myocytes. Cardiovasc Res. 1993 Sep;27(9):1580-91. [2]. Spinelli W,et al. Effects of WAY-123,398, a new class III antiarrhythmic agent, on cardiac refractoriness and ventricular fibrillation threshold in anesthetized dogs: a comparison with UK-68798, E-4031, and dl-sotalol. J Cardiovasc Pharmacol. 1992 Dec;20(6):913-22.

Description

WAY-123398 is a class III antiarrhythmic agent. WAY-123398 is a selective blocker of the delayed rectifier K+ current[1].

Related Catalog

Research Areas >> Cardiovascular Disease

Signaling Pathways >> Others >> Others

References

Density	1.36g/cm3
Boiling Point	637.9ºC at 760 mmHg
Molecular Formula	C₁₉H₂₅N₅O₄S₂
Molecular Weight	451.56300
Flash Point	339.6ºC
Exact Mass	451.13500
PSA	121.37000
LogP	3.93630
Vapour Pressure	3.57E-16mmHg at 25°C
Index of Refraction	1.638
InChIKey	PELVIWZRAPOYAC-UHFFFAOYSA-N
SMILES	CN(CCN(C)S(=O)(=O)c1ccc(NS(C)(=O)=O)cc1)c1nc2ccccc2n1C

N-methyl-N-<2-<methyl(1-methyl-1H-benzimidazol-2-yl)amino>ethyl>-4-<(methylsulfonyl)amino>benzenesulfonamide

N-Methyl-N-(2-(methyl(1-methyl-1H-benzimidazol-2-yl)amino)ethyl)-4-((methylsulfonyl)amino)benzenesulfonamide hcl

Way-123,398

Benzenesulfonamide,N-methyl-N-(2-(methyl(1-methyl-1H-benzimidazol-2-yl)amino)ethyl)-4-((methylsulfonyl)amino)