THR-18
Modify Date: 2025-08-25 15:07:27
THR-18 structure
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Common Name | THR-18 | ||
|---|---|---|---|---|
| CAS Number | 1383452-03-6 | Molecular Weight | 2390.7742 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C105H167F3N28O28S2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of THR-18THR-18 is an 18-mer peptide derived from the sequence of human plasminogen activator inhibitor 1 (PAI-1), having the ability to bind to a site of tissue plasminogen activator (tPA) distal to its catalytic site and uncouple the beneficial clot-dissolving properties of tPA from its deleterious non-fibrinolytic effects. |
| Name | THR-18 |
|---|
| Description | THR-18 is an 18-mer peptide derived from the sequence of human plasminogen activator inhibitor 1 (PAI-1), having the ability to bind to a site of tissue plasminogen activator (tPA) distal to its catalytic site and uncouple the beneficial clot-dissolving properties of tPA from its deleterious non-fibrinolytic effects. |
|---|
| Molecular Formula | C105H167F3N28O28S2 |
|---|---|
| Molecular Weight | 2390.7742 |
| InChIKey | UNDAPMUKULIMSY-HGKXDEPLSA-N |
| SMILES | CCC(C)C(NC(=O)C(CCC(=O)O)NC(=O)C(CCC(=O)O)NC(=O)C1CCCN1C(=O)C(C)NC(=O)C(CCSC)NC(=O)C(CCCNC(=N)N)NC(C)=O)C(=O)NC(C(=O)NC(CCSC)C(=O)NC(CC(=O)O)C(=O)NC(CCCNC(=N)N)C(=O)N1CCCC1C(=O)NC(Cc1ccccc1)C(=O)NC(CC(C)C)C(=O)NC(Cc1ccc(O)cc1)C(=O)NC(C(=O)NC(C(=O)NC(CCCNC(=N)N)C(N)=O)C(C)C)C(C)C)C(C)CC.O=C(O)C(F)(F)F |