Odiparcil

Modify Date: 2024-01-01 18:11:41

Odiparcil Structure
Odiparcil structure
Common Name Odiparcil
CAS Number 137215-12-4 Molecular Weight 324.34900
Density N/A Boiling Point N/A
Molecular Formula C15H16O6S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Odiparcil


Odiparcil (SB-424323) is an orally active beta-d-thioxyloside analog with antithrombotic activity associated with a reduced risk of adverse bleeding events. Odiparcil (SB-424323) is indirect thrombin inhibitor that exerts its anticoagulant effect through activation of antithrombin II (heparin cofactor II) [1][2].

 Names

Name 4-methyl-7-[(5-thio-beta-D-xylopyranosyl)oxy]-2H-1-benzopyran-2-one

 Odiparcil Biological Activity

Description Odiparcil (SB-424323) is an orally active beta-d-thioxyloside analog with antithrombotic activity associated with a reduced risk of adverse bleeding events. Odiparcil (SB-424323) is indirect thrombin inhibitor that exerts its anticoagulant effect through activation of antithrombin II (heparin cofactor II) [1][2].
Related Catalog
Target

Thrombin[2]

References

[1]. Myers AL, et al. Characterization of total plasma glycosaminoglycan levels in healthy volunteers following oral administration of a novel antithrombotic odiparcil with aspirin or enoxaparin. J Clin Pharmacol. 2008 Oct;48(10):1158-70

[2]. Levy JH, et al. Novel oral anticoagulants: implications in the perioperative setting. Anesthesiology. 2010 Sep;113(3):726-45.

 Chemical & Physical Properties

Molecular Formula C15H16O6S
Molecular Weight 324.34900
Exact Mass 324.06700
PSA 125.43000
LogP 0.63580
Vapour Pressure 1.03E-13mmHg at 25°C
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