PF05020182

Modify Date: 2024-09-06 13:27:29

PF05020182 Structure
PF05020182 structure
 Common Name PF05020182
CAS Number 1354712-92-7 Molecular Weight 366.455
Density 1.2±0.1 g/cm3 Boiling Point N/A
Molecular Formula C18H30N4O4 Melting Point N/A
MSDS USA Flash Point N/A

 Use of PF05020182


PF05020182 is novel potent and selective Kv7.2/4 potassium channel opener. PF-05020182 (2) significantly inhibits convulsions in the MES assay at doses tested, consistent with in vitro activity measure. The physiochemical properties, in vitro and in vivo activities of PF-05020182 support further development as an adjunctive treatment of refractory epilepsy. Facilitating activation, or delaying inactivation, of the native Kv7 channel reduces neuronal excitability, which may be beneficial in controlling spontaneous electrical activity during epileptic seizures.

 Names

Name PF-05020182
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Molecular Formula C18H30N4O4
Molecular Weight 366.455
Exact Mass 366.226715
LogP 4.42
Index of Refraction 1.534

 Safety Information

RIDADR NONH for all modes of transport

 Synonyms

N-[4,6-Dimethoxy-2-(4-methoxy-1-piperidinyl)-5-pyrimidinyl]-3,3-dimethylbutanamide
N-[4,6-Dimethoxy-2-(4-methoxy-1-piperidinyl)-5-pyrimidinyl]-3,3-dimethyl-butanamide
Butanamide, N-[4,6-dimethoxy-2-(4-methoxy-1-piperidinyl)-5-pyrimidinyl]-3,3-dimethyl-
PF-05020182
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Related Compounds: More...
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Chemsrc provides PF05020182(CAS#:1354712-92-7) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of PF05020182 are included as well.>> amp version: PF05020182

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