Monomethyl auristatin E intermediate-6

Modify Date: 2025-08-25 13:35:18

Monomethyl auristatin E intermediate-6 structure	Common Name	Monomethyl auristatin E intermediate-6
	CAS Number	135383-54-9	Molecular Weight	363.45
	Density	1.088±0.06 g/cm3(Predicted)	Boiling Point	476.6±35.0 °C(Predicted)
	Molecular Formula	C₂₀H₂₉NO₅	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Monomethyl auristatin E intermediate-6

Monomethyl auristatin E intermediate-6 is an intermediate reagent in the synthesis of Monomethyl auristatin E (HY-15162). Monomethyl auristatin E (MMAE) is a microtubule/tubulin inhibitor with anticancer activity. MMAE is widely used as the cytotoxic component (ADC Cytotoxin) of antibody-drug conjugates (ADCs)[1].

Name	obdxbuwpbdvkeb-kssfioaisa-n

Description	Monomethyl auristatin E intermediate-6 is an intermediate reagent in the synthesis of Monomethyl auristatin E (HY-15162). Monomethyl auristatin E (MMAE) is a microtubule/tubulin inhibitor with anticancer activity. MMAE is widely used as the cytotoxic component (ADC Cytotoxin) of antibody-drug conjugates (ADCs)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
References	[1]. Lisa Buckel, et al. Tumor radiosensitization by monomethyl auristatin E: mechanism of action and targeted delivery. Cancer Res. 2015 Apr 1;75(7):1376-87.

Density	1.088±0.06 g/cm3(Predicted)
Boiling Point	476.6±35.0 °C(Predicted)
Molecular Formula	C₂₀H₂₉NO₅
Molecular Weight	363.45
InChIKey	OBDXBUWPBDVKEB-KSSFIOAISA-N
SMILES	CCC(C)C(NC(=O)OCc1ccccc1)C(=O)CC(=O)OC(C)(C)C

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Monomethyl auristatin E intermediate-6

Use of Monomethyl auristatin E intermediate-6

Names

Monomethyl auristatin E intermediate-6 Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.