Orismilast

Modify Date: 2024-01-03 19:31:24

Orismilast Structure
Orismilast structure
Common Name Orismilast
CAS Number 1353546-86-7 Molecular Weight 510.29
Density 1.7±0.1 g/cm3 Boiling Point 788.8±60.0 °C at 760 mmHg
Molecular Formula C19H15Cl2F2NO7S Melting Point N/A
MSDS N/A Flash Point 430.9±32.9 °C

 Use of Orismilast


Orismilast (LEO-32731) is a PDE4 inhibitor used for the research of inflammatory diseases[1].

 Names

Name Leo-32731
Synonym More Synonyms

 Orismilast Biological Activity

Description Orismilast (LEO-32731) is a PDE4 inhibitor used for the research of inflammatory diseases[1].
Related Catalog
References

[1]. Nielsen,et al.Preparation of benzodioxole or benzodioxepine heterocyclic compounds as phosphodiesterase inhibitors.WO2011160632A1.

 Chemical & Physical Properties

Density 1.7±0.1 g/cm3
Boiling Point 788.8±60.0 °C at 760 mmHg
Molecular Formula C19H15Cl2F2NO7S
Molecular Weight 510.29
Flash Point 430.9±32.9 °C
Exact Mass 508.991425
LogP 0.82
Vapour Pressure 0.0±2.8 mmHg at 25°C
Index of Refraction 1.649

 Synonyms

Leo-32731
Ethanone, 2-(3,5-dichloro-1-oxido-4-pyridinyl)-1-[7-(difluoromethoxy)-2',3',5',6'-tetrahydro-1',1'-dioxidospiro[1,3-benzodioxole-2,4'-[4H]thiopyran]-4-yl]-
2-(3,5-Dichloro-1-oxido-4-pyridinyl)-1-[7-(difluoromethoxy)-1',1'-dioxido-2',3',5',6'-tetrahydrospiro[1,3-benzodioxole-2,4'-thiopyran]-4-yl]ethanone
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