9-(3-fluoro-2-phosphonylmethoxypropyl)adenine

Modify Date: 2025-08-27 19:13:28

9-(3-fluoro-2-phosphonylmethoxypropyl)adenine structure	Common Name	9-(3-fluoro-2-phosphonylmethoxypropyl)adenine
	CAS Number	135295-27-1	Molecular Weight	305.20300
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₉H₁₃FN₅O₄P	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of 9-(3-fluoro-2-phosphonylmethoxypropyl)adenine

(2RS)-FPMPA can be used for synthesis of antiretroviral agents against HIV-1 and HIV-2[1].

Name	(1-(6-amino-9H-purin-9-yl)-3-fluoropropan-2-yloxy)methylphosphonic acid
Synonym	More Synonyms

Description	(2RS)-FPMPA can be used for synthesis of antiretroviral agents against HIV-1 and HIV-2[1].
Related Catalog	Signaling Pathways >> Anti-infection >> HIV Research Areas >> Infection
References	[1]. Balzarini J, et al. 9-[(2RS)-3-fluoro-2-phosphonylmethoxypropyl] derivatives of purines: a class of highly selective antiretroviral agents in vitro and in vivo. Proc Natl Acad Sci U S A. 1991 Jun 1;88(11):4961-5.

Molecular Formula	C₉H₁₃FN₅O₄P
Molecular Weight	305.20300
Exact Mass	305.06900
PSA	146.19000
LogP	0.47960
InChIKey	BFZJTDBFUROXJA-UHFFFAOYSA-N
SMILES	Nc1ncnc2c1ncn2CC(CF)OCP(=O)(O)O

9-(RS)-(3-fluoro-2-phosphonomethoxypropyl)adenine

RS-FPMPA

9-(3-Fluoro-2-phosphonylmethoxypropyl)-adenine

[2-(6-Amino-purin-9-yl)-1-fluoromethyl-ethoxymethyl]-phosphonic acid

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