1-(t-Boc-Aminooxy)-3-aminooxy-propane

Modify Date: 2024-02-19 19:26:20

1-(t-Boc-Aminooxy)-3-aminooxy-propane Structure
1-(t-Boc-Aminooxy)-3-aminooxy-propane structure
Common Name 1-(t-Boc-Aminooxy)-3-aminooxy-propane
CAS Number 1352546-80-5 Molecular Weight 206.24
Density N/A Boiling Point N/A
Molecular Formula C8H18N2O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 1-(t-Boc-Aminooxy)-3-aminooxy-propane


1-(t-Boc-Aminooxy)-3-aminooxy-propane is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name 1-(t-Boc-Aminooxy)-3-aminooxy-propane
Synonym More Synonyms

 1-(t-Boc-Aminooxy)-3-aminooxy-propane Biological Activity

Description 1-(t-Boc-Aminooxy)-3-aminooxy-propane is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C8H18N2O4
Molecular Weight 206.24

 Synonyms

MFCD28397120
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