S-acetyl-PEG6

Modify Date: 2024-01-10 05:53:52

S-acetyl-PEG6 Structure
S-acetyl-PEG6 structure
Common Name S-acetyl-PEG6
CAS Number 1352221-63-6 Molecular Weight 340.433
Density 1.1±0.1 g/cm3 Boiling Point 441.7±45.0 °C at 760 mmHg
Molecular Formula C14H28O7S Melting Point N/A
MSDS N/A Flash Point 220.9±28.7 °C

 Use of S-acetyl-PEG6


S-acetyl-PEG6 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name S-acetyl-PEG6-alcohol
Synonym More Synonyms

 S-acetyl-PEG6 Biological Activity

Description S-acetyl-PEG6 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Density 1.1±0.1 g/cm3
Boiling Point 441.7±45.0 °C at 760 mmHg
Molecular Formula C14H28O7S
Molecular Weight 340.433
Flash Point 220.9±28.7 °C
Exact Mass 340.155579
LogP -1.41
Vapour Pressure 0.0±2.4 mmHg at 25°C
Index of Refraction 1.480

 Synonyms

S-(17-Hydroxy-3,6,9,12,15-pentaoxaheptadec-1-yl) ethanethioate
Ethanethioic acid, S-(17-hydroxy-3,6,9,12,15-pentaoxaheptadec-1-yl) ester
MFCD22574786
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