EIPA hydrochloride

Modify Date: 2025-09-18 11:49:41

EIPA hydrochloride structure	Common Name	EIPA hydrochloride
	CAS Number	1345839-28-2	Molecular Weight	336.22
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₁H₁₉Cl₂N₇O	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of EIPA hydrochloride

EIPA hydrochloride (L593754 hydrochloride) is a TRPP3 channel inhibitor with an IC50 of 10.5 μM[1]. EIPA also inhibits Na+/H+-exchanger (NHE)[2] and macropinocytosis[3].

Name	EIPA hydrochloride

Description	EIPA hydrochloride (L593754 hydrochloride) is a TRPP3 channel inhibitor with an IC50 of 10.5 μM[1]. EIPA also inhibits Na+/H+-exchanger (NHE)[2] and macropinocytosis[3].
Related Catalog	Signaling Pathways >> Membrane Transporter/Ion Channel >> Sodium Channel Signaling Pathways >> Membrane Transporter/Ion Channel >> TRP Channel Research Areas >> Cancer Research Areas >> Inflammation/Immunology
Target	IC50: 10.5 μM (TRPP3 channel)[1] NHE[2] Macropinocytosis[3]
References	[1]. Dai XQ, et al. Inhibition of TRPP3 channel by amiloride and analogs. Mol Pharmacol. 2007 Dec;72(6):1576-85. [2]. Shi H, et al. Na+/H+ Exchanger Regulates Amino Acid-Mediated Autophagy in Intestinal Epithelial Cells. Cell Physiol Biochem. 2017;42(6):2418-2429. [3]. Zhu BY, et al. A new HDAC inhibitor cinnamoylphenazine shows antitumor activity in association with intensive macropinocytosis.

Molecular Formula	C₁₁H₁₉Cl₂N₇O
Molecular Weight	336.22
Storage condition	2-8℃

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: EIPA hydrochloride
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Purity: 99.0%
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Price: ￥1089/10 mM * 1 mL in DMSO

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