CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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TL1570000
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CHEMICAL NAME :
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Piperazine, 1-(8-chloro-10,11-dihydrodibenzo(b,f)thiepin-10-yl)-4 -methyl-
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CAS REGISTRY NUMBER :
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13448-22-1
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LAST UPDATED :
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198910
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DATA ITEMS CITED :
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2
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MOLECULAR FORMULA :
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C19-H21-Cl-N2-S
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MOLECULAR WEIGHT :
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344.93
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WISWESSER LINE NOTATION :
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T C676 BS&T&J FG I- AT6N DNTJ D1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Oral
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SPECIES OBSERVED :
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Rodent - mouse
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DOSE/DURATION :
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78 mg/kg
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TOXIC EFFECTS :
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Behavioral - ataxia
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REFERENCE :
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CCCCAK Collection of Czechoslovak Chemical Communications. (Academic Press Inc. Ltd., 24-28 Oval Rd., London NW1 7DX, UK) V.1- 1929- Volume(issue)/page/year: 48,144,1983 ** REPRODUCTIVE DATA **
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Oral
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DOSE :
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1080 mg/kg
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SEX/DURATION :
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female 2-19 day(s) after conception
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TOXIC EFFECTS :
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Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)
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REFERENCE :
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THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris, France) V.1- 1946- Volume(issue)/page/year: 22,1429,1967
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