DCVC

Modify Date: 2024-01-14 15:24:35

DCVC structure	Common Name	DCVC
	CAS Number	13419-46-0	Molecular Weight	216.08600
	Density	1.544g/cm3	Boiling Point	339.7ºC at 760mmHg
	Molecular Formula	C₅H₇Cl₂NO₂S	Melting Point	N/A
	MSDS	N/A	Flash Point	159.2ºC

Use of DCVC

DCVC inhibits pathogen-stimulated TNF-α in human extra placental membranes in vitro.Target: TNF-αin vitro: DCVC inhibits pathogen stimulated cytokine release from tissue punch cultures. DCVC (5-50 μM) significantly inhibits LTA-, LPS-, and GBS-stimulated cytokine release from tissue cultures as early as 4 h (P ≤ 0.05). In contrast, TCA (up to 500 μM) does not inhibit LTA-stimulated cytokine release from tissue punches. DCVC effects on LTA-stimulated and LPS-stimulated TNF-α release from tissue punch cultures of extraplacental membranes. DCVC effects on GBS-stimulated release of pro-inflammatory cytokines from extraplacental membranes in transwell cultures.

Name	2-amino-3-[(E)-1,2-dichloroethenyl]sulfanylpropanoic acid
Synonym	More Synonyms

Description	DCVC inhibits pathogen-stimulated TNF-α in human extra placental membranes in vitro.Target: TNF-αin vitro: DCVC inhibits pathogen stimulated cytokine release from tissue punch cultures. DCVC (5-50 μM) significantly inhibits LTA-, LPS-, and GBS-stimulated cytokine release from tissue cultures as early as 4 h (P ≤ 0.05). In contrast, TCA (up to 500 μM) does not inhibit LTA-stimulated cytokine release from tissue punches. DCVC effects on LTA-stimulated and LPS-stimulated TNF-α release from tissue punch cultures of extraplacental membranes. DCVC effects on GBS-stimulated release of pro-inflammatory cytokines from extraplacental membranes in transwell cultures.
Related Catalog	Signaling Pathways >> Apoptosis >> TNF Receptor Research Areas >> Infection
References	[1]. Boldenow E, et al. The trichloroethylene metabolite S-(1,2-dichlorovinyl)-l-cysteine but not trichloroacetate inhibits pathogen-stimulated TNF-α in human extraplacental membranes in vitro. Reprod Toxicol. 2015 Apr;52:1-6. [2]. Lash LH, et al. Multigenerational study of chemically induced cytotoxicity and proliferation in cultures of human proximal tubular cells. Int J Mol Sci. 2014 Nov 18;15(11):21348-65. [3]. Yoo HS, et al. Comparative analysis of the relationship between trichloroethylene metabolism and tissue-specific toxicity among inbred mouse strains: kidney effects. J Toxicol Environ Health A. 2015;78(1):32-49.

Description

Related Catalog

Signaling Pathways >> Apoptosis >> TNF Receptor

Research Areas >> Infection

References

[1]. Boldenow E, et al. The trichloroethylene metabolite S-(1,2-dichlorovinyl)-l-cysteine but not trichloroacetate inhibits pathogen-stimulated TNF-α in human extraplacental membranes in vitro. Reprod Toxicol. 2015 Apr;52:1-6.

[2]. Lash LH, et al. Multigenerational study of chemically induced cytotoxicity and proliferation in cultures of human proximal tubular cells. Int J Mol Sci. 2014 Nov 18;15(11):21348-65.

[3]. Yoo HS, et al. Comparative analysis of the relationship between trichloroethylene metabolism and tissue-specific toxicity among inbred mouse strains: kidney effects. J Toxicol Environ Health A. 2015;78(1):32-49.

Density	1.544g/cm3
Boiling Point	339.7ºC at 760mmHg
Molecular Formula	C₅H₇Cl₂NO₂S
Molecular Weight	216.08600
Flash Point	159.2ºC
Exact Mass	214.95700
PSA	88.62000
LogP	2.10830
Vapour Pressure	1.66E-05mmHg at 25°C
Index of Refraction	1.6
Storage condition	2-8℃

HS Code	2930909090

L-cysteine

CAS#:52-90-4

Trichloroethylene

CAS#:79-01-6

DCVC

CAS#:13419-46-0

Literature: McKinney et al. Journal of the American Chemical Society, 1959 , vol. 81, p. 909,913

Precursor 2
CAS#:52-90-4 L-cysteine CAS#:79-01-6 Trichloroethylene
DownStream 0

HS Code	2930909090
Summary	2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

DCVC

S-((E)-1,2-Dichlor-vinyl)-L-cystein

S-((E)-1,2-dichloro-vinyl)-L-cysteine

(E)-S-(1,2-Dichloroethenyl)-L-cysteine

L-Cysteine,S-(1,2-dichloroethenyl)-,(E)-(9CI)

ALANINE,3-((1,2-DICHLOROVINYL)THIO)-,(E)-L

L-Cysteine,S-((1E)-1,2-dichloroethenyl)

L-Cysteine,S-(1,2-dichloroethenyl)-,(E)

S-(1,2-dichlorovinyl)-L-cysteine

S-(trans-1,2-Dichlorovinyl)-L-cysteine

S-(1,2-Dichlorovinyl)cysteine

DC Chemicals Limited
China
Product Name: DCVC
Price: $Inquiry/250mg $585.0/10mg $1685.0/50mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: S-(E-1,2-DICHLOROVINYL)-L-CYSTEINE
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

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DCVC

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