EBOV-IN-1
Modify Date: 2025-08-27 08:57:48
EBOV-IN-1 structure
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Common Name | EBOV-IN-1 | ||
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| CAS Number | 1335113-30-8 | Molecular Weight | 573.72 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C34H43N3O5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of EBOV-IN-1EBOV-IN-1 (com 3.47) is an adamantane dipeptide piperazine and an inhibitor of Ebola virus (EBOV). EBOV-IN-1 targets Niemann-Pick C1 (NPC1) and inhibits its binding to the EBOV glycoprotein (GP) that activates and mediates viral penetration into host cells, thereby inhibiting EBOV infection. EBOV-IN-1 inhibits pseudotyped EBOV infection with an IC50 of 13 nM[1]. |
| Name | EBOV-IN-1 |
|---|
| Description | EBOV-IN-1 (com 3.47) is an adamantane dipeptide piperazine and an inhibitor of Ebola virus (EBOV). EBOV-IN-1 targets Niemann-Pick C1 (NPC1) and inhibits its binding to the EBOV glycoprotein (GP) that activates and mediates viral penetration into host cells, thereby inhibiting EBOV infection. EBOV-IN-1 inhibits pseudotyped EBOV infection with an IC50 of 13 nM[1]. |
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| Related Catalog | |
| References |
| Molecular Formula | C34H43N3O5 |
|---|---|
| Molecular Weight | 573.72 |
| InChIKey | KSISWIVDFITFKQ-UHFFFAOYSA-N |
| SMILES | COC(=O)c1ccc(COc2ccccc2CN2CCN(C(=O)CNC(=O)CC34CC5CC(CC(C5)C3)C4)CC2)cc1 |