EBOV-IN-1
Modify Date: 2024-01-12 18:34:44
EBOV-IN-1 structure
|
Common Name | EBOV-IN-1 | ||
|---|---|---|---|---|
| CAS Number | 1335113-30-8 | Molecular Weight | 573.72 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C34H43N3O5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of EBOV-IN-1EBOV-IN-1 (com 3.47) is an adamantane dipeptide piperazine and an inhibitor of Ebola virus (EBOV). EBOV-IN-1 targets Niemann-Pick C1 (NPC1) and inhibits its binding to the EBOV glycoprotein (GP) that activates and mediates viral penetration into host cells, thereby inhibiting EBOV infection. EBOV-IN-1 inhibits pseudotyped EBOV infection with an IC50 of 13 nM[1]. |
| Name | EBOV-IN-1 |
|---|
| Description | EBOV-IN-1 (com 3.47) is an adamantane dipeptide piperazine and an inhibitor of Ebola virus (EBOV). EBOV-IN-1 targets Niemann-Pick C1 (NPC1) and inhibits its binding to the EBOV glycoprotein (GP) that activates and mediates viral penetration into host cells, thereby inhibiting EBOV infection. EBOV-IN-1 inhibits pseudotyped EBOV infection with an IC50 of 13 nM[1]. |
|---|---|
| Related Catalog | |
| References |
| Molecular Formula | C34H43N3O5 |
|---|---|
| Molecular Weight | 573.72 |