vinaxanthone
Modify Date: 2025-08-25 13:58:18
vinaxanthone structure
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Common Name | vinaxanthone | ||
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| CAS Number | 133293-89-7 | Molecular Weight | 576.41800 | |
| Density | 1.772g/cm3 | Boiling Point | 1064.4ºC at 760mmHg | |
| Molecular Formula | C28H16O14 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 357.6ºC | |
Use of vinaxanthoneVinaxanthone (SM-345431) is a potent and selective semaphorin3A inhibitor. Vinaxanthone exhibits semaphorin3A inhibiting activity with an IC50 of 0.1-0.2 μM[1]. Vinaxanthone shows selective inhibitory activity against phospholipase C (PLC) from rat brain, mutine colon 26 Adenocarcinoma and murine fibroblasts NIH3T3 with IC50s being 5.4, 9.3 and 44 μM, respectively[2]. |
| Name | 5,7-diacetyl-6-(5-carboxy-6,7-dihydroxy-4-oxochromen-3-yl)-2,3-dihydroxy-9-oxoxanthene-1-carboxylic acid |
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| Synonym | More Synonyms |
| Description | Vinaxanthone (SM-345431) is a potent and selective semaphorin3A inhibitor. Vinaxanthone exhibits semaphorin3A inhibiting activity with an IC50 of 0.1-0.2 μM[1]. Vinaxanthone shows selective inhibitory activity against phospholipase C (PLC) from rat brain, mutine colon 26 Adenocarcinoma and murine fibroblasts NIH3T3 with IC50s being 5.4, 9.3 and 44 μM, respectively[2]. |
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| Related Catalog | |
| References |
| Density | 1.772g/cm3 |
|---|---|
| Boiling Point | 1064.4ºC at 760mmHg |
| Molecular Formula | C28H16O14 |
| Molecular Weight | 576.41800 |
| Flash Point | 357.6ºC |
| Exact Mass | 576.05400 |
| PSA | 250.08000 |
| LogP | 3.34360 |
| Vapour Pressure | 0mmHg at 25°C |
| Index of Refraction | 1.768 |
| InChIKey | MEYYEMQDVMMNNR-UHFFFAOYSA-N |
| SMILES | CC(=O)c1cc2c(=O)c3c(C(=O)O)c(O)c(O)cc3oc2c(C(C)=O)c1-c1coc2cc(O)c(O)c(C(=O)O)c2c1=O |
| Vinaxanthone |
| 411F |