Debio 0617B
Modify Date: 2024-01-10 19:18:44
Debio 0617B structure
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Common Name | Debio 0617B | ||
|---|---|---|---|---|
| CAS Number | 1332329-27-7 | Molecular Weight | 581.976 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C28H23ClF3N7O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Debio 0617BDebio 0617B, a multi-kinase inhibitor, reduces maintenance and self-renewal of primary human AML CD34+ stem/progenitor cells. Debio 0617B has a unique profile targeting key kinases upstream of STAT3/STAT5 signaling such as JAK, SRC, ABL, and class III/V receptor tyrosine kinases (TKs). Debio 0617B has documented efficacy in STAT3-driven solid tumors[1]. |
| Name | Debio 0617B |
|---|---|
| Synonym | More Synonyms |
| Description | Debio 0617B, a multi-kinase inhibitor, reduces maintenance and self-renewal of primary human AML CD34+ stem/progenitor cells. Debio 0617B has a unique profile targeting key kinases upstream of STAT3/STAT5 signaling such as JAK, SRC, ABL, and class III/V receptor tyrosine kinases (TKs). Debio 0617B has documented efficacy in STAT3-driven solid tumors[1]. |
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| Related Catalog | |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Molecular Formula | C28H23ClF3N7O2 |
| Molecular Weight | 581.976 |
| Exact Mass | 581.155396 |
| LogP | 4.03 |
| Index of Refraction | 1.659 |
| N-{4-Chloro-3-[2-{[4-(methylcarbamoyl)phenyl]amino}-7,8-dihydropyrido[4,3-d]pyrimidin-6(5H)-yl]phenyl}-4-(trifluoromethyl)-2-pyridinecarboxamide |
| MFCD30749186 |
| 2-Pyridinecarboxamide, N-[4-chloro-3-[7,8-dihydro-2-[[4-[(methylamino)carbonyl]phenyl]amino]pyrido[4,3-d]pyrimidin-6(5H)-yl]phenyl]-4-(trifluoromethyl)- |