Olopatadine-d3 (hydrochloride)

Modify Date: 2024-01-16 15:01:08

Olopatadine-d3 (hydrochloride) structure	Common Name	Olopatadine-d3 (hydrochloride)
	CAS Number	1331635-21-2	Molecular Weight	376.892
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₁H₂₁D₃ClNO₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Olopatadine-d3 (hydrochloride)

Olopatadine-d3 hydrochloride (ALO4943A-d3) is the deuterium labeled Olopatadine hydrochloride. Olopatadine hydrochloride (ALO4943A) is a histamine blocker used to treat allergic conjunctivitis[1][2].

Name	Olopatadine-d3 (hydrochloride)
Synonym	More Synonyms

Description	Olopatadine-d3 hydrochloride (ALO4943A-d3) is the deuterium labeled Olopatadine hydrochloride. Olopatadine hydrochloride (ALO4943A) is a histamine blocker used to treat allergic conjunctivitis[1][2].
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> Histamine Receptor Research Areas >> Endocrinology Research Areas >> Inflammation/Immunology Signaling Pathways >> GPCR/G Protein >> Histamine Receptor
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Tamura, T., et al., Effect of olopatadine and other histamine H1 receptor antagonists on the skin inflammation induced by repeated topical application of oxazolone in mice. Pharmacology, 2005. 75(1): p. 45-52. [3]. Ohmori, K., et al., Pharmacological, pharmacokinetic and clinical properties of olopatadine hydrochloride, a new antiallergic drug. Jpn J Pharmacol, 2002. 88(4): p. 379-97. [4]. Yanni, J.M., et al., The in vitro and in vivo ocular pharmacology of olopatadine (AL-4943A), an effective anti-allergic/antihistaminic agent. J Ocul Pharmacol Ther, 1996. 12(4): p. 389-400.

Molecular Formula	C₂₁H₂₁D₃ClNO₃
Molecular Weight	376.892
Exact Mass	376.163300

Olopatadine-d3 (hydrochloride)

Dibenz[b,e]oxepin-2-acetic acid, 6,11-dihydro-11-[3-(methylmethyl-d3-amino)propylidene]-, (11E)-, hydrochloride (1:1)

[(11E)-11-(3-{Methyl[(2H3)methyl]amino}propylidene)-6,11-dihydrodibenzo[b,e]oxepin-2-yl]acetic acid hydrochloride (1:1)

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Olopatadine-d3 (hydrochloride)
Price: Negotiable
Purity: 99.0%
Delivery: 10 Day
Contact: Huang
Email: sales@echemcloud.com

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Olopatadine-d3 (hydrochloride)

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