Etofenamate-d4

Modify Date: 2023-01-16 08:09:48

Etofenamate-d4 structure	Common Name	Etofenamate-d4
	CAS Number	1329837-73-1	Molecular Weight	373.360
	Density	1.3±0.1 g/cm3	Boiling Point	451.1±45.0 °C at 760 mmHg
	Molecular Formula	C₁₈H₁₄D₄F₃NO₄	Melting Point	N/A
	MSDS	N/A	Flash Point	226.6±28.7 °C

Use of Etofenamate-d4

Etofenamate-d4 is the deuterium labeled Etofenamate. Etofenamate, a non-steroid anti-inflammatory drug (NSAID) and a non-selective COX inhibitor, possesses analgesic, anti-rheumatic, antipyretic and anti-inflammatory properties. Etofenamate is used in the research for osteoarthritis, arthritis and other inflammatory diseases[1][2][3].

Name	Etofenamate-d4
Synonym	More Synonyms

Description	Etofenamate-d4 is the deuterium labeled Etofenamate. Etofenamate, a non-steroid anti-inflammatory drug (NSAID) and a non-selective COX inhibitor, possesses analgesic, anti-rheumatic, antipyretic and anti-inflammatory properties. Etofenamate is used in the research for osteoarthritis, arthritis and other inflammatory diseases[1][2][3].
Related Catalog	Research Areas >> Inflammation/Immunology Signaling Pathways >> Immunology/Inflammation >> COX
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [2]. Bender T, Bariska J, Rojkovich B, Bálint G. Etofenamate levels in human serum and synovial fluid following iontophoresis. Arzneimittelforschung. 2001;51(6):489-92. [3]. Fraga A, de Almeida M, Moreira-da-Silva V et al. Intramuscular Etofenamate versus Diclofenac in the Relief of Renal Colic : A Randomised, Single-Blind, Comparative Study. Clin Drug Investig. 2003;23(11):701-6. [4]. Joana Marto, et al. Topical gels of etofenamate: in vitro and in vivo evaluation. Pharm Dev Technol. 2015;20(6):710-5.

Density	1.3±0.1 g/cm3
Boiling Point	451.1±45.0 °C at 760 mmHg
Molecular Formula	C₁₈H₁₄D₄F₃NO₄
Molecular Weight	373.360
Flash Point	226.6±28.7 °C
Exact Mass	373.143890
LogP	4.14
Vapour Pressure	0.0±1.2 mmHg at 25°C
Index of Refraction	1.552

2-(2-Hydroxyethoxy)ethyl 2-{[3-(trifluoromethyl)phenyl]amino}(2H4)benzoate

Etofenamate-d4

Benzoic-2,3,4,5-d4 acid, 6-[[3-(trifluoromethyl)phenyl]amino]-, 2-(2-hydroxyethoxy)ethyl ester

Etofenamate-d4

Use of Etofenamate-d4

Names

Etofenamate-d4 Biological Activity

Chemical & Physical Properties

Synonyms