Xanthurenic acid-d4

Modify Date: 2025-08-25 09:51:38

Xanthurenic acid-d4 Structure
Xanthurenic acid-d4 structure
Common Name Xanthurenic acid-d4
CAS Number 1329611-28-0 Molecular Weight 209.191
Density 1.6±0.1 g/cm3 Boiling Point 514.4±50.0 °C at 760 mmHg
Molecular Formula C10H3D4NO4 Melting Point N/A
MSDS N/A Flash Point 264.9±30.1 °C

 Use of Xanthurenic acid-d4


Xanthurenic acid-d4 is the deuterium labeled Xanthurenic acid[1]. Xanthurenic acid is a putative endogenous Group II metabotropic glutamate receptor agonist, on sensory transmission in the thalamus[2].

 Names

Name 4,8-Dihydroxy-2-(2H4)quinolinecarboxylic acid
Synonym More Synonyms

 Xanthurenic acid-d4 Biological Activity

Description Xanthurenic acid-d4 is the deuterium labeled Xanthurenic acid[1]. Xanthurenic acid is a putative endogenous Group II metabotropic glutamate receptor agonist, on sensory transmission in the thalamus[2].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Copeland CS, et al. Actions of Xanthurenic acid, a putative endogenous Group II metabotropic glutamate receptor agonist, on sensory transmission in the thalamus. Neuropharmacology. 2013 Mar;66:133-42.  

 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Boiling Point 514.4±50.0 °C at 760 mmHg
Molecular Formula C10H3D4NO4
Molecular Weight 209.191
Flash Point 264.9±30.1 °C
Exact Mass 209.062622
LogP 2.64
Vapour Pressure 0.0±1.4 mmHg at 25°C
Index of Refraction 1.779

 Synonyms

2-Quinoline-3,5,6,7-d4-carboxylic acid, 4,8-dihydroxy-
4,8-Dihydroxy-2-(2H4)quinolinecarboxylic acid
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